Paromomycin
11 interactions
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 11, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Aspirin
Aspirin Rectal
Cefepime Injection
Colistimethate Injection
Emtricitabine
Exenatide Injection
Major
Paromomycin Aspirin Acuprin® Increased aspirin exposure and an increased risk of nephrotoxicity Details Paromomycin Aspirin Rectal Aspirin Increased aspirin exposure and an increased risk of nephrotoxicity Details Paromomycin Cefepime Injection Maxipime® An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Paromomycin Colistimethate Injection Coly-Mycin M® Respiratory depression Details Paromomycin Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Paromomycin Exenatide Injection Bydureon Reduced oral antibiotics absorption and reduced efficacy of oral antibiotics Details Paromomycin Foscarnet Injection Foscavir Nephrotoxicity Details Paromomycin Furosemide Injection Disal An increased risk of ototoxicity Details Paromomycin Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Paromomycin Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... DetailsNo interactions on this page match that filter — try the next page or clear the filter.
Check another drug
Still have questions about this combination?
Every question gets a real answer from a licensed pharmacist — free, and usually within a day.
Ask the pharmacistEducational information only, not medical advice. Always confirm interactions with your pharmacist
or prescriber before making any change to your medications.