Finerenone

218 interactions 1 explained in plain English 246 cited references

Also sold as: Kerendia Kerendia®

About Finerenone

Finerenone is a mineralocorticoid receptor antagonist used to slow kidney damage in adults with chronic kidney disease from type 2 diabetes. Read the full Finerenone drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Levoketoconazole Indinavir Idelalisib Ketoconazole Itraconazole Lonafarnib

27 Contraindicated 180 Major 11 Moderate

All (218) Contraindicated (27) Major (180) Moderate (11)

Contraindicated

Finerenone Adagrasib Krazati Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Boceprevir Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Ceritinib Zykadia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Clarithromycin Biaxin Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Cobicistat Tybost Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Ensitrelvir Increased finerenone exposure and an increased risk of hyperkalemia, hypotension and hyponatremia Details Finerenone Idelalisib Zydelig Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Indinavir Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Itraconazole Sporanox Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Ketoconazole Extina Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Levoketoconazole Recorlev Increased CYP3A4 substrate exposure and an increased risk of sensitive CYP3A4 substrate-related adverse reaction Details Finerenone Lonafarnib Zokinvy Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Mifepristone Korlym Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Nefazodone Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Nelfinavir Viracept Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Nirmatrelvir Increased finerenone exposure and increased risk of serious adverse effects (hyperkalemia, hypotension and hyponatremia) Details Finerenone Paritaprevir Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Posaconazole Noxafil Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Ribociclib Kisqali Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Ritonavir Norvir Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Saquinavir Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Telaprevir Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Telithromycin Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Troleandomycin Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Tucatinib Tukysa Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Voriconazole Vfend Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Ketoconazole Topical Extina® Foam Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details

Major

Finerenone Asciminib Scemblix Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Azithromycin AzaSite Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Belumosudil Rezurock Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Bicalutamide Casodex Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Atorvastatin Atorvaliq Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Amlodipine Amvaz® Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Brodalumab Injection Siliq Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Clotrimazole Aardora Anti-Fungal Maximum Strength Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Clotrimazole Lozenge Mycelex® Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Clotrimazole Topical Cruex Antifungal Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Clotrimazole Vaginal Gyne-Lotrimin 3® Cream Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Cyclosporine Injection Atopica Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Finerenone Cyclosporine Ophthalmic Cequa Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.