Trimethoprim

Contraindicated

Trimethoprim Dofetilide Tikosyn Increased dofetilide exposure and an increased risk of QT interval prolongation, and an increased risk of torsades de pointes Details

Major

Trimethoprim Amitriptyline Elavil Explained An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Lisinopril Prinivil Explained Increased risk of hyperkalemia Details Trimethoprim Arsenic Trioxide Trisenox Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Arsenic Trioxide Injection Trisenox Cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Azathioprine Azasan Increased risk of bone marrow suppression and an increased risk of myelosuppression Details Trimethoprim Benazepril Lotensin Increased risk of hyperkalemia Details Trimethoprim Azilsartan Edarbi Increased risk of hyperkalemia Details Trimethoprim Candesartan Atacand Increased risk of hyperkalemia Details Trimethoprim Captopril Capoten® Increased risk of hyperkalemia Details Trimethoprim Chloroquine Aralen® Increased chloroquine exposure and increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Cyclosporine Injection Atopica Increased nephrotoxicity and an increased risk of renal dysfunction Details Trimethoprim Cyclosporine Ophthalmic Cequa Increased nephrotoxicity and an increased risk of renal dysfunction Details Trimethoprim Digoxin Cardoxin® An increased digoxin exposure Details Trimethoprim Disopyramide Norpace An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Dolasetron Anzemet An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Dolasetron Injection Anzemet An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Enalapril Epaned Increased risk of hyperkalemia Details Trimethoprim Eprosartan Teveten® Increased risk of hyperkalemia Details Trimethoprim Exenatide Injection Bydureon Reduced oral antibiotics absorption and reduced efficacy of oral antibiotics Details Trimethoprim Flecainide Tambocor® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Folic Acid Folacin Reduced folic acid exposure Details Trimethoprim Foscarnet Injection Foscavir An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Fosinopril Monopril® Increased risk of hyperkalemia Details Trimethoprim Gemifloxacin Factive An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Irbesartan Avapro Increased risk of hyperkalemia Details Trimethoprim Isradipine DynaCirc® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Leucovorin Vykoura Reduced efficacy of trimethoprim/sulfamethoxazole Details Trimethoprim Leucovorin Injection Vykoura Reduced efficacy of trimethoprim/sulfamethoxazole Details Trimethoprim Loperamide Diamode An increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Trimethoprim Losartan Arbli Increased risk of hyperkalemia Details Trimethoprim Mefloquine Lariam® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Mercaptopurine Purinethol® Increased risk of bone marrow suppression and an increased risk of myelosuppression Details Trimethoprim Metformin Fortamet® Increased metFORMIN exposure and an increased risk of lactic acidosis Details Trimethoprim Methotrexate Jylamvo An increased methotrexate exposure, an increased risk of methotrexate toxicity or methotrexate-related severe adverse reactions, r... Details Trimethoprim Methotrexate Injection Abitrexate® An increased methotrexate exposure, an increased risk of methotrexate toxicity or methotrexate-related severe adverse reactions, r... Details Trimethoprim Moexipril Univasc® Increased risk of hyperkalemia Details Trimethoprim Octreotide Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Octreotide Injection Bynfezia An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Trimethoprim Olmesartan Benicar Increased risk of hyperkalemia Details