Ketoconazole

Contraindicated

Ketoconazole Sertraline Explained Increased sertraline exposure and an increased risk of QT interval prolongation Details Ketoconazole Buprenorphine Belbuca Explained Increased buprenorphine exposure, an increased risk of buprenorphine-related adverse events and an increased risk of QT interval p... Details Ketoconazole Colchicine Colcrys Explained Increased colchicine exposure and an increased risk of colchicine toxicity Details Ketoconazole Simvastatin Flolipid Explained Increased simvastatin exposure and an increased risk of myopathy or rhabdomyolysis Details Ketoconazole Aripiprazole Injection Abilify Increased ARIPiprazole exposure and an increased risk of QT interval prolongation Details Ketoconazole Alfuzosin UroXatral Increased alfuzosin exposure and an increased risk of QT interval prolongation Details Ketoconazole Bedaquiline Sirturo Increased bedaquiline exposure and an increased risk for QT interval prolongation Details Ketoconazole Dihydroergotamine Injection DHE-45® Injection Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Ketoconazole Dihydroergotamine Nasal Spray Migranal Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Ketoconazole Dofetilide Tikosyn Increased dofetilide exposure, an increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) and an i... Details Ketoconazole Encorafenib Braftovi Increased encorafenib exposure, an increased risk of encorafenib-related adverse events and an increased risk of QT interval prolo... Details Ketoconazole Entrectinib Rozlytrek Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details Ketoconazole Felodipine Plendil® Increased felodipine exposure and additive negative inotropic effect Details Ketoconazole Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Ketoconazole Glasdegib Daurismo Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details Ketoconazole Irinotecan Camptosar Increased irinotecan exposure and an increased irinotecan active metabolite exposure Details Ketoconazole Irinotecan Injection Camptosar Increased irinotecan exposure and an increased irinotecan active metabolite exposure Details Ketoconazole Irinotecan Lipid Complex Injection Onivyde® Increased irinotecan exposure and an increased irinotecan active metabolite exposure Details Ketoconazole Ivabradine Corlanor Increased ivabradine exposure, an increased risk of ivabradine-related adverse effects and an increased risk of QT prolongation Details Ketoconazole Lefamulin Xenleta Increased lefamulin exposure, an increased risk of lefamulin-related adverse reactions and an increased risk of QT interval prolon... Details Ketoconazole Loperamide Diamode Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details Ketoconazole Lovastatin Altocor® Increased lovastatin exposure and an increased risk of myopathy or rhabdomyolysis Details Ketoconazole Lurasidone Latuda Increased lurasidone exposure Details Ketoconazole Methylergonovine Methergine Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Ketoconazole Midazolam Nasal Spray Nayzilam Increased midazolam exposure and potentially increased midazolam toxicity (excessive sedation and prolonged hypnotic effects) Details Ketoconazole Midazolam Injection Nayzilam Increased midazolam exposure and potentially increased midazolam toxicity (excessive sedation and prolonged hypnotic effects) Details Ketoconazole Naloxegol Movantik Increased naloxegol exposure and an increased risk of naloxegol-related adverse effects Details Ketoconazole Nimodipine Nimotop Increased niMODipine exposure Details Ketoconazole Nisoldipine Sular Increased nisoldipine exposure Details

Major

Ketoconazole Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine and morphine exposure Details Ketoconazole Omeprazole Gastrobim Explained Reduced ketoconazole exposure, reduced efficacy of ketoconazole, increased omeprazole exposure and an increased risk of omeprazole... Details Ketoconazole Amitriptyline Elavil Explained An increased risk for QT interval prolongation Details Ketoconazole Relugolix Orgovyx Explained Increased relugolix exposure and an increased risk of QT interval prolongation Details Ketoconazole Abemaciclib Verzenio Explained Increased abemaciclib exposure Details Ketoconazole Acalabrutinib Calquence Increased acalabrutinib exposure Details Ketoconazole Ado-Trastuzumab Emtansine Injection KADCYLA Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ketoconazole Aliskiren Tekturna Increased aliskiren exposure and an increased risk of aliskiren-related adverse reactions Details Ketoconazole Amisulpride Injection Barhemsys Increased risk of QT interval prolongation Details Ketoconazole Apixaban Eliquis Explained Increased apixaban exposure and an increased risk of bleeding Details Ketoconazole Arsenic Trioxide Trisenox Increased risk for QT interval prolongation Details