Fluvoxamine

113 interactions 10 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Fluvoxamine Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of serotonin syndrome, increased codeine and increased or reduced active metabolite (morphine) exposure Details Fluvoxamine Amitriptyline Elavil Explained Increased tricyclic antidepressant exposure and an increased risk of serotonin syndrome Details Fluvoxamine Sertraline Explained An increased risk of serotonin syndrome Details Fluvoxamine Buprenorphine Belbuca Explained An increased risk of serotonin syndrome, increased buprenorphine exposure and an increased risk of buprenorphine-related adverse e... Details Fluvoxamine Relugolix Orgovyx Explained Increased relugolix exposure Details Fluvoxamine Abrocitinib Cibinqo Explained Increased abrocitinib and active metabolite exposure Details Fluvoxamine Acalabrutinib Calquence Increased acalabrutinib exposure and increased risk of toxicity Details Fluvoxamine Apixaban Eliquis Explained Increased apixaban exposure and increased risk of bleeding Details Fluvoxamine Asenapine Transdermal Patch Secuado Increased asenapine exposure and an increased fluvoxaMINE exposure Details Fluvoxamine Aspirin Acuprin® An increased risk of bleeding Details Fluvoxamine Aspirin Rectal Aspirin An increased risk of bleeding Details Fluvoxamine Betrixaban Bevyxxa® An increased risk of bleeding Details Fluvoxamine Aficamten Increased aficamten exposure and an increased risk of aficamten-related adverse reaction Details Fluvoxamine Anagrelide Agrylin Increased anagrelide exposure and increased risk of bleeding Details Fluvoxamine Bedaquiline Sirturo Increased bedaquiline exposure Details Fluvoxamine Bendamustine Injection Belrapzo Increased bendamustine exposure and an increased risk of bendamustine-related adverse effects Details Fluvoxamine Bosutinib Bosulif Increased bosutinib exposure Details Fluvoxamine Brigatinib Alunbrig Increased brigatinib exposure Details Fluvoxamine Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Fluvoxamine Budesonide Entocort Increased budesonide exposure Details Fluvoxamine Budesonide Nasal Spray Rhinocort Increased budesonide exposure Details Fluvoxamine Budesonide Oral Inhalation Pulmicort Increased budesonide exposure Details Fluvoxamine Butorphanol Injection Butorphic Increased risk of serotonin syndrome Details Fluvoxamine Butorphanol Nasal Spray Stadol® NS Increased risk of serotonin syndrome Details Fluvoxamine Clopidogrel Plavix Reduced clopidogrel active metabolite exposure, reduced platelet inhibition and an increased risk of bleeding Details Fluvoxamine Cyclosporine Injection Atopica Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Fluvoxamine Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Fluvoxamine Dabigatran Pradaxa® Increased dabigatran exposure and an increased risk of bleeding Details Fluvoxamine Dabigatran Etexilate Increased dabigatran exposure and an increased risk of bleeding Details Fluvoxamine Dalteparin Injection Fragmin An increased risk of bleeding Details Fluvoxamine Deflazacort Emflaza Increased exposure to active metabolite of deflazacort Details Fluvoxamine Diazepam Nasal Spray Valtoco Increased diazePAM and N-desmethyldiazePAM exposure Details Fluvoxamine Diazepam Rectal Diastat Increased diazePAM and N-desmethyldiazePAM exposure Details Fluvoxamine Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Fluvoxamine Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Fluvoxamine Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.