Glasdegib

288 interactions 319 cited references

Also sold as: Daurismo Daurismo®

About Glasdegib

Glasdegib is used along with cytarabine as a first treatment for acute myeloid leukemia (AML; a type of cancer that begins in the white blood cells) in people over 75 years of age, or in adults who have other medical conditions and can not be treated with other chemotherapy medications. Glasdegib is in a class of medic… Read the full Glasdegib drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Dronedarone Ensitrelvir Bepridil Bacillus Of Calmette And Guerin Vaccine, Live Dengue Tetravalent Vaccine, Live Cisapride

26 Contraindicated 259 Major 3 Moderate

All (288) Contraindicated (26) Major (259) Moderate (3)

Contraindicated

Glasdegib Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Glasdegib Bepridil An increased risk of QT interval prolongation Details Glasdegib Cisapride Propulsid® Increased risk of QT interval prolongation Details Glasdegib Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Glasdegib Dronedarone Multaq Increased risk of QT interval prolongation Details Glasdegib Ensitrelvir Increased CYP3A substrates exposure and an increased risk of CYP3A substrates-related adverse effects Details Glasdegib Fluconazole Diflucan Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details Glasdegib Ketoconazole Extina Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details Glasdegib Levoketoconazole Recorlev An increased risk of QT interval prolongation and torsades pointes, an increased CYP3A4 substrate exposure and an increased risk o... Details Glasdegib Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Glasdegib Mesoridazine An increased risk of QT interval prolongation Details Glasdegib Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Glasdegib Pimozide An increased risk of QT interval prolongation Details Glasdegib Piperaquine An increased risk of QT interval prolongation Details Glasdegib Posaconazole Noxafil Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details Glasdegib Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Glasdegib Saquinavir An increased risk of QT interval prolongation Details Glasdegib Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Glasdegib Sparfloxacin An increased risk of QT interval prolongation Details Glasdegib Terfenadine An increased risk of QT interval prolongation Details Glasdegib Thioridazine An increased risk of QT interval prolongation Details Glasdegib Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Glasdegib Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Glasdegib Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details Glasdegib Ziprasidone Geodon An increased risk of QT interval prolongation Details Glasdegib Ketoconazole Topical Extina® Foam Increased CYP3A4 substrate exposure and an increased risk of QT interval prolongation Details

Major

Glasdegib Abametapir Increased exposure of CYP3A4 substrate Details Glasdegib Amitriptyline Elavil Increased risk of QT interval prolongation Details Glasdegib Sertraline Increased risk of QT interval prolongation Details Glasdegib Buprenorphine Belbuca Increased risk of QT interval prolongation Details Glasdegib Relugolix Orgovyx Increased risk of QT interval prolongation Details Glasdegib Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Glasdegib Arsenic Trioxide Trisenox Increased risk of QT interval prolongation Details Glasdegib Aripiprazole Injection Abilify Increased risk of QT interval prolongation Details Glasdegib Arsenic Trioxide Injection Trisenox Increased risk of QT interval prolongation Details Glasdegib Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Glasdegib Azithromycin AzaSite Increased risk of QT interval prolongation Details Glasdegib Alfuzosin UroXatral Increased risk of QT interval prolongation Details Glasdegib Anagrelide Agrylin Increased risk of QT interval prolongation Details Glasdegib Bedaquiline Sirturo Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.