Flumazenil

Name: Flumazenil Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

4 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 8, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Diazepam Nasal Spray Diazepam Rectal Midazolam Nasal Spray Midazolam Injection

4 Contraindicated

All (4) Contraindicated (4)

Contraindicated

Flumazenil Diazepam Nasal Spray Valtoco Increased risk of serious adverse effects in patients who are physically dependent on benzodiazepines, including seizures Details Flumazenil Diazepam Rectal Diastat Increased risk of serious adverse effects in patients who are physically dependent on benzodiazepines, including seizures Details Flumazenil Midazolam Nasal Spray Nayzilam Increased risk of serious adverse effects in patients who are physically dependent on benzodiazepines, including seizures Details Flumazenil Midazolam Injection Nayzilam Increased risk of serious adverse effects in patients who are physically dependent on benzodiazepines, including seizures Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.