Ethchlorvynol

22 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Hydromorphone Rectal Buprenorphine Butorphanol Injection Nalbuphine Injection Fentanyl Transdermal Patch Linezolid Injection
21 Major 1 Moderate
All (22) Major (21) Moderate (1)

Major

Ethchlorvynol Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Ethchlorvynol Buprenorphine Belbuca Explained An increased risk of respiratory depression and CNS depression Details Ethchlorvynol Butorphanol Injection Butorphic Increased risk of respiratory and CNS depression Details Ethchlorvynol Butorphanol Nasal Spray Stadol® NS Increased risk of respiratory and CNS depression Details Ethchlorvynol Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Ethchlorvynol Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Ethchlorvynol Diazepam Nasal Spray Valtoco Additive respiratory depression Details Ethchlorvynol Diazepam Rectal Diastat Additive respiratory depression Details Ethchlorvynol Esketamine Nasal Spray Spravato Increased risk of sedation Details Ethchlorvynol Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Ethchlorvynol Hydromorphone Injection Dilaudid Increased risk of respiratory and CNS depression Details Ethchlorvynol Hydromorphone Rectal available generically Increased risk of respiratory and CNS depression Details Ethchlorvynol Lacosamide Injection Motpoly An increased risk of CNS depression Details Ethchlorvynol Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Ethchlorvynol Linezolid Injection Zyvox An increased risk of respiratory depression Details Ethchlorvynol Metoclopramide Injection Gimoti Increased risk of CNS depression Details Ethchlorvynol Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Ethchlorvynol Midazolam Nasal Spray Nayzilam Additive respiratory depression Details Ethchlorvynol Midazolam Injection Nayzilam Additive respiratory depression Details Ethchlorvynol Morphine Injection Astramorph® PF Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Ethchlorvynol Nalbuphine Injection Nubain® Increased risk of respiratory and CNS depression Details

Moderate

Ethchlorvynol Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.