Fondaparinux Injection

180 interactions 288 cited references

Also sold as: Arixtra Arixtra®

About Fondaparinux Injection

Fondaparinux injection is used to prevent deep vein thrombosis (DVT; a blood clot, usually in the leg), which can lead to pulmonary embolism (PE; a blood clot in the lung), in people who are having hip surgery, hip or knee replacement, or abdominal surgery. It is also used in along with warfarin (Coumadin, Jantoven) to… Read the full Fondaparinux Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Abciximab Aceclofenac Acemetacin Alipogene Tiparvovec Alteplase, Recombinant

1 Contraindicated 137 Major 40 Moderate 2 Minor

All (180) Contraindicated (1) Major (137) Moderate (40) Minor (2)

Contraindicated

Fondaparinux Injection Defibrotide Increased risk of bleeding Details

Major

Fondaparinux Injection Abciximab An increased risk of bleeding Details Fondaparinux Injection Aceclofenac An increased risk of bleeding Details Fondaparinux Injection Acemetacin An increased risk of bleeding Details Fondaparinux Injection Alipogene Tiparvovec An increased risk of bleeding Details Fondaparinux Injection Alteplase, Recombinant Activase An increased risk of bleeding Details Fondaparinux Injection Amtolmetin Guacil An increased risk of bleeding Details Fondaparinux Injection Anagrelide Agrylin Increased risk of bleeding Details Fondaparinux Injection Anistreplase An increased risk of bleeding Details Fondaparinux Injection Apixaban Eliquis An increased risk of bleeding and can cause serious, potentially fatal bleeding Details Fondaparinux Injection Argatroban Increased risk of bleeding Details Fondaparinux Injection Aspirin Acuprin® Increased risk of bleeding Details Fondaparinux Injection Bemiparin Increased risk of bleeding Details Fondaparinux Injection Betrixaban Bevyxxa® Increased risk of bleeding Details Fondaparinux Injection Bivalirudin Angiomax Increased risk of bleeding Details Fondaparinux Injection Bromfenac Bromsite An increased risk of bleeding Details Fondaparinux Injection Bufexamac An increased risk of bleeding Details Fondaparinux Injection Cangrelor Kengreal Increased risk of bleeding Details Fondaparinux Injection Caplacizumab-Yhdp An increased risk of bleeding Details Fondaparinux Injection Celecoxib Celebrex An increased risk of bleeding Details Fondaparinux Injection Chamomile Increased risk of bleeding Details Fondaparinux Injection Choline Salicylate An increased risk of bleeding Details Fondaparinux Injection Cilostazol Pletal® Increased risk of bleeding Details Fondaparinux Injection Citalopram Celexa An increased risk of bleeding Details Fondaparinux Injection Clonixin An increased risk of bleeding Details Fondaparinux Injection Clopidogrel Plavix Increased risk of bleeding Details Fondaparinux Injection Collagenase, Clostridium Histolyticum Increased risk of bleeding adverse effects Details Fondaparinux Injection Curcumin An increased risk of bleeding Details Fondaparinux Injection Dabigatran Etexilate An increased risk of bleeding Details Fondaparinux Injection Dalteparin Fragmin Increased risk of bleeding Details Fondaparinux Injection Danaparoid Increased risk of bleeding Details Fondaparinux Injection Desvenlafaxine Pristiq An increased risk of bleeding Details Fondaparinux Injection Dexibuprofen An increased risk of bleeding Details Fondaparinux Injection Dexketoprofen An increased risk of bleeding Details Fondaparinux Injection Diclofenac Aleve Arthritis Pain An increased risk of bleeding Details Fondaparinux Injection Diflunisal Dolobid An increased risk of bleeding Details Fondaparinux Injection Dipyridamole Permole® Increased risk of bleeding Details Fondaparinux Injection Dipyrone An increased risk of bleeding Details Fondaparinux Injection Donanemab-Azbt An increased risk of amyloid related imaging abnormalities (ARIA), or intracerebral hemorrhage Details Fondaparinux Injection Doxycycline Acticlate An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.