Selegiline

Contraindicated

Selegiline Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of serotonin syndrome Details Selegiline Amitriptyline Elavil Explained Neurotoxicity, seizures, or serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes) Details Selegiline Sertraline Explained An increased risk of serotonin syndrome (hypertension, tachycardia, hyperthermia, myoclonus, mental status changes) or CNS toxicit... Details Selegiline Deutetrabenazine Austedo Hypertensive crisis (headache, hyperpyrexia, hypertension) Details Selegiline Diethylpropion Tenuate Hypertensive crisis (headache, hyperpyrexia, hypertension) Details Selegiline Linezolid Injection Zyvox Hypertensive crisis (headache, palpitation, neck stiffness) or seizure Details Selegiline Maprotiline Ludiomil® An increased risk of severe or life threatening reactions, like neurotoxicity, seizures Details Selegiline Methyldopa Aldomet® Hypertensive crisis (headache, palpitation, neck stiffness) Details Selegiline Methylphenidate Adhansia XR® An increased risk of hypertensive crisis (headache, palpitation, and neck stiffness) Details Selegiline Methylphenidate Transdermal Patch Daytrana An increased risk of hypertensive crisis (headache, palpitation, and neck stiffness) Details Selegiline Morphine Injection Astramorph® PF Increased risk of the CNS and respiratory depressant effects of morphine and an increased risk of serotonin syndrome Details

Major

Selegiline Albuterol Oral Inhalation Accuneb® Explained An increased risk of cardiovascular adverse effects Details Selegiline Buprenorphine Belbuca Explained An increased risk of serotonin syndrome or opioid-related toxicity Details Selegiline Atropine Ophthalmic Atropine Care 1% Potential to cause hypertensive crisis Details Selegiline Butorphanol Injection Butorphic Increased risk of serotonin syndrome or opioid toxicity Details Selegiline Butorphanol Nasal Spray Stadol® NS Increased risk of serotonin syndrome or opioid toxicity Details Selegiline Dolasetron Anzemet Increased risk of serotonin syndrome Details Selegiline Dolasetron Injection Anzemet Increased risk of serotonin syndrome Details Selegiline Fentanyl Transdermal Patch Duragesic® Potentiation of opioid effects and an increased risk of serotonin syndrome Details Selegiline Granisetron Transdermal Patch Sancuso Increased risk of serotonin syndrome Details Selegiline Granisetron Injection Granisol Increased risk of serotonin syndrome Details Selegiline Hydromorphone Injection Dilaudid Increased risk of serotonin syndrome or opioid toxicity Details Selegiline Hydromorphone Rectal available generically Increased risk of serotonin syndrome or opioid toxicity Details Selegiline Levodopa Oral Inhalation Inbrija Increased risk of levodopa adverse effects, including severe orthostatic hypotension Details Selegiline Lithium Carbonate Lithobid Increased risk of serotonin syndrome Details Selegiline Metoclopramide Injection Gimoti Increased risk of hypertensive crisis Details Selegiline Metoclopramide Nasal Spray Gimoti Increased risk of hypertensive crisis Details Selegiline Nalbuphine Injection Nubain® Increased risk of serotonin syndrome or opioid toxicity Details Selegiline Olodaterol Oral Inhalation Striverdi Potentiated cardiovascular effects Details Selegiline Palonosetron Injection Aloxi® An increased risk of serotonin syndrome Details

Moderate

Selegiline Acarbose Prandase® Explained An increased risk of hypoglycemia Details Selegiline Dexamethasone Injection Decadron Reduced selegiline exposure Details Selegiline Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced selegiline exposure Details Selegiline Dopamine Increased hypertensive effects Details Selegiline Estradiol Delestrogen An increase in selegiline oral bioavailability and an increased risk of selegiline adverse reactions Details Selegiline Estradiol Topical Divigel An increase in selegiline oral bioavailability and an increased risk of selegiline adverse reactions Details Selegiline Estradiol Transdermal Patch Alora® An increase in selegiline oral bioavailability and an increased risk of selegiline adverse reactions Details Selegiline Glimepiride Amaryl An increased risk of hypoglycemia Details Selegiline Glipizide Glucotrol An increased risk of hypoglycemia Details Selegiline Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details