Desoximetasone Topical

29 interactions 136 cited references
Also sold as: Topicort Topicort LP® Topicort®
About Desoximetasone Topical

Desoximetasone topical is used to treat the redness, swelling, itching, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes develop red, scaly rashes… Read the full Desoximetasone Topical drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Desoximetasone Topical Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Desoximetasone Topical Bemiparin Increased risk of bleeding Details Desoximetasone Topical Carbamazepine Carbatrol Reduced corticosteroids exposure and reduced efficacy of corticosteroids Details Desoximetasone Topical Cosyntropin False elevations of plasma cortisol levels Details Desoximetasone Topical Ethinyl Estradiol Increased corticosteroid exposure Details Desoximetasone Topical Fosphenytoin Cerebyx Reduced corticosteroid exposure Details Desoximetasone Topical Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Desoximetasone Topical Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Desoximetasone Topical Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Desoximetasone Topical Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Desoximetasone Topical Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Desoximetasone Topical Nadroparin Increased risk of bleeding Details Desoximetasone Topical Phenytoin Dilantin Reduced corticosteroid exposure Details Desoximetasone Topical Rabies Vaccine Imovax An inadequate immunological response to the vaccine, an increased risk of altered immunocompetence and reduced immune response to... Details Desoximetasone Topical Relacorilant Lifyorli Reduced relacorilant exposure and reduced efficacy of relacorilant, reduced glucocorticoids exposure and reduced efficacy of gluco... Details Desoximetasone Topical Sargramostim Leukine Increased myeloproliferative effects of sargramostim Details Desoximetasone Topical Somatrogon-Ghla Reduced serum cortisol exposure, an increased risk of central (secondary) hypoadrenalism and attenuated growth-promoting effects o... Details Desoximetasone Topical Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.