Bleomycin

21 interactions 515 cited references
Also sold as: Blenoxane®
About Bleomycin

Bleomycin is a chemotherapy antibiotic used to treat several cancers including head and neck, testicular, cervical, and lymphomas. Read the full Bleomycin drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Measles Virus Vaccine, Live Brentuximab Vedotin Injection Rubella Virus Vaccine, Live Mumps Virus Vaccine, Live Bacillus Of Calmette And Guerin Vaccine, Live Brentuximab Vedotin
11 Contraindicated 10 Major
All (21) Contraindicated (11) Major (10)

Contraindicated

Bleomycin Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Bleomycin Brentuximab Vedotin Increased risk of pulmonary toxicity Details Bleomycin Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Bleomycin Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bleomycin Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bleomycin Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bleomycin Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Bleomycin Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Bleomycin Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bleomycin Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details Bleomycin Brentuximab Vedotin Injection Adcetris Increased risk of pulmonary toxicity Details

Major

Bleomycin Ascorbic Acid (Vitamin C) C-500® Chewable Tablet Decreased bleomycin efficacy Details Bleomycin Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Bleomycin Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Bleomycin Ascorbic Acid Decreased bleomycin efficacy Details Bleomycin Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Bleomycin Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Bleomycin Fosphenytoin Cerebyx Reduced phenytoin or fosphenytoin (prodrug of phenytoin) exposure Details Bleomycin Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Bleomycin Phenytoin Dilantin Reduced phenytoin or fosphenytoin (prodrug of phenytoin) exposure Details Bleomycin Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.