Cyclosporine
174 interactions 14 explained in plain English
Also sold as:
Atopica
Cequa
Cyclavance
Gengraf
Modulis
Neoral
Optimmune
Restasis
Sandimmune
Sporimune
Verkazia
Vevye
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Contraindicated
Cyclosporine Colchicine Colcrys Explained Increased colchicine and cycloSPORINE exposure Details Cyclosporine Simvastatin Flolipid Explained An increased risk of myopathy or rhabdomyolysis Details Cyclosporine Ezetimibe Zetia Increased ezetimibe and cycloSPORINE exposure and an increased risk of ezetimibe and cycloSPORINE-related adverse effects DetailsMajor
Cyclosporine Acetaminophen And Codeine Capital® & Codeine Explained Increased codeine and morphine exposure Details Cyclosporine Abametapir Explained Increased exposure of CYP3A4 substrate Details Cyclosporine Lisinopril Prinivil Explained Acute renal dysfunction and an increased risk of hyperkalemia Details Cyclosporine Buprenorphine Belbuca Explained Increased buprenorphine exposure and an increased risk of buprenorphine-related adverse events Details Cyclosporine Relugolix Orgovyx Explained Increased relugolix exposure Details Cyclosporine Abrocitinib Cibinqo Explained Increased exposure of P-glycoprotein substrate Details Cyclosporine Acalabrutinib Calquence Increased acalabrutinib exposure and increased risk of toxicity Details Cyclosporine Adalimumab Injection Abrilada Altered cycloSPORINE exposure Details Cyclosporine Aliskiren Tekturna Increased aliskiren exposure and plasma concentrations Details Cyclosporine Alpelisib Piqray Increased alpelisib exposure and an increased risk of alpelisib-related adverse effects and toxicity Details Cyclosporine Ambrisentan Letairis Increased ambrisentan exposure Details Cyclosporine Apixaban Eliquis Explained Increased apixaban exposure and increased risk of bleeding Details Cyclosporine Asciminib Scemblix Increased exposure to CYP3A4/P-gp substrates and increased risk of CYP3A4/P-gp substrates-related adverse effects Details Cyclosporine Aspirin Acuprin® An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Aspirin Rectal Aspirin An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Atogepant Qulipta Increased atogepant exposure Details Cyclosporine Azathioprine Azasan Reduced cycloSPORINE exposure and an increased risk of hepatotoxicity Details Cyclosporine Azithromycin AzaSite Increased cycloSPORINE exposure Details Cyclosporine Belumosudil Rezurock Explained Increased P-gp substrate exposure Details Cyclosporine Betrixaban Bevyxxa® Increased betrixaban exposure and increased risk of bleeding Details Cyclosporine Benazepril Lotensin Acute renal dysfunction and an increased risk of hyperkalemia Details Cyclosporine Atorvastatin Atorvaliq Increased atorvastatin exposure, an increased risk of myopathy or rhabdomyolysis and an increased cycloSPORINE exposure Details Cyclosporine Afatinib Gilotrif Increased exposure of afatinib Details Cyclosporine Alogliptin Nesina Increased cycloSPORINE exposure Details Cyclosporine Amlodipine Amvaz® Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Amphotericin B Injection Abelcet An increased risk of renal dysfunction Details Cyclosporine Azilsartan Edarbi An increased risk of hyperkalemia Details Cyclosporine Bedaquiline Sirturo Increased bedaquiline exposure Details Cyclosporine Bosutinib Bosulif Increased bosutinib exposure Details Cyclosporine Brigatinib Alunbrig Increased brigatinib exposure Details Cyclosporine Bromfenac Ophthalmic Bromday® An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Budesonide Entocort Increased budesonide exposure Details Cyclosporine Budesonide Nasal Spray Rhinocort Increased budesonide exposure Details Cyclosporine Budesonide Oral Inhalation Pulmicort Increased budesonide exposure Details Cyclosporine Canagliflozin Invokana Increased cycloSPORINE exposure Details Cyclosporine Capmatinib Tabrecta Increased cycloSPORINE exposure Details Cyclosporine Captopril Capoten® Acute renal dysfunction, increased risk of hyperkalemia and an increased cycloSPORINE exposure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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