Cyclosporine

Major

Cyclosporine Caspofungin Injection Cancidas Increased plasma levels of caspofungin and increased risk of hepatic enzyme elevations Details Cyclosporine Cyclophosphamide Cytoxan® Decreased serum cycloSPORINE concentration Details Cyclosporine Cyclophosphamide Injection Cytoxan® Injection Decreased serum cycloSPORINE concentration Details Cyclosporine Dabigatran Pradaxa® Increased dabigatran exposure Details Cyclosporine Dabigatran Etexilate Increased dabigatran exposure Details Cyclosporine Deflazacort Emflaza Increased exposure to active metabolite of deflazacort Details Cyclosporine Dexamethasone Injection Decadron Reduced cycloSPORINE exposure Details Cyclosporine Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced cycloSPORINE exposure Details Cyclosporine Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Diclofenac Transdermal Patch Flector An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Digoxin Cardoxin® Increased digoxin exposure and an increased risk of digoxin toxicity Details Cyclosporine Doxorubicin Adriamycin Increased DOXOrubicin exposure and an increased risk of DOXOrubicin-related adverse reactions Details Cyclosporine Edoxaban Savaysa Increased edoxaban exposure Details Cyclosporine Elacestrant Orserdu Increased elacestrant/cycloSPORINE exposure and an increased risk of elacestrant/cycloSPORINE-related adverse effects Details Cyclosporine Eluxadoline Viberzi Increased eluxadoline and/or cyclosporine exposure Details Cyclosporine Enalapril Epaned Acute renal dysfunction and an increased risk of hyperkalemia Details Cyclosporine Enasidenib Idhifa Reduced CYP3A substrate exposure and reduced efficacy of CYP3A substrate Details Cyclosporine Encorafenib Braftovi Reduced CYP3A4 substrate exposure and reduced efficacy of CYP3A4 substrate Details Cyclosporine Entrectinib Rozlytrek Increased cycloSPORINE exposure Details Cyclosporine Eprosartan Teveten® An increased risk of hyperkalemia Details Cyclosporine Erdafitinib Balversa Increased P-gp substrate exposure and an increased risk of P-gp substrate-related adverse effects Details Cyclosporine Estradiol Delestrogen Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Estradiol Topical Divigel Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Estradiol Transdermal Patch Alora® Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Etodolac Lodine An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Felodipine Plendil® Increased felodipine exposure, increased risk of felodipine toxicity and increased cycloSPORINE exposure Details Cyclosporine Fenoprofen Fenopron An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Fentanyl Transdermal Patch Duragesic® Increased fentaNYL exposure and an increased risk of prolonged opioid effects Details Cyclosporine Finerenone Kerendia Increased finerenone exposure and an increased risk of finerenone-related adverse effects Details Cyclosporine Flurbiprofen Ansaid An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Flurbiprofen Ophthalmic Ocufen An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Fluvastatin Lescol Increased fluvastatin exposure and an increased risk of myopathy or rhabdomyolysis Details Cyclosporine Foscarnet Injection Foscavir Nephrotoxicity Details Cyclosporine Fosinopril Monopril® Acute renal dysfunction and an increased risk of hyperkalemia Details Cyclosporine Fostamatinib Tavalisse Increased cycloSPORINE exposure Details Cyclosporine Gemfibrozil Lopid Increased risk of renal dysfunction Details Cyclosporine Gentamicin Injection Garamycin® I.V. An increased risk of nephrotoxicity and increased risk of renal dysfunction Details Cyclosporine Gentamicin Ophthalmic Garamycin® Ophthalmic An increased risk of nephrotoxicity and increased risk of renal dysfunction Details