Cyclosporine

Major

Cyclosporine Gentamicin Topical Garamycin® An increased risk of nephrotoxicity and increased risk of renal dysfunction Details Cyclosporine Gilteritinib Xospata Increased P-gp substrate exposure and increased incidence and severity of adverse reactions associated with the P-gp substrate Details Cyclosporine Hydrocortisone Ala-Cort Increased hydrocortisone exposure, an increased cycloSPORINE exposure and an increased risk of convulsions Details Cyclosporine Hydrocortisone Injection A-Hydrocort® Increased hydrocortisone exposure, an increased cycloSPORINE exposure and an increased risk of convulsions Details Cyclosporine Hydroxychloroquine Plaquenil Increased cycloSPORINE exposure and an increased risk of seizures Details Cyclosporine Ibrexafungerp Brexafemme Increased cycloSPORINE exposure Details Cyclosporine Ibrutinib Imbruvica Increased ibrutinib exposure Details Cyclosporine Ibuprofen Addaprin An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Infigratinib Truseltiq Increased infigratinib plasma concentrations Details Cyclosporine Irbesartan Avapro An increased risk of hyperkalemia Details Cyclosporine Istradefylline Nourianz Increased cycloSPORINE exposure Details Cyclosporine Ketoconazole Topical Extina® Foam An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Ketoprofen Actron® An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ketorolac Acular An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ketorolac Injection Acular An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ketorolac Nasal Spray Sprix An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Ketorolac Ophthalmic Acular An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Lanreotide Injection Somatuline Decrease the relative bioavailability of cycloSPORINE Details Cyclosporine Lefamulin Xenleta Increased lefamulin exposure, an increased risk of lefamulin-related adverse reactions, increased cycloSPORINE exposure and an inc... Details Cyclosporine Lenacapavir Injection Sunlenca Increased sensitive P-gp/CYP3A substrate exposure and an increased risk of sensitive P-gp/CYP3A substrate-related adverse effects Details Cyclosporine Lenacapavir Oral Sunlenca Increased sensitive P-gp/CYP3A substrate exposure and an increased risk of sensitive P-gp/CYP3A substrate-related adverse effects Details Cyclosporine Letermovir Injection Prevymis Increased cycloSPORINE exposure and an increased letermovir exposure Details Cyclosporine Levonorgestrel After banger Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Levonorgestrel Intrauterine System Kyleena Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Loperamide Diamode An increased loperamide exposure and an increased risk of loperamide-related adverse reactions Details Cyclosporine Losartan Arbli An increased risk of hyperkalemia Details Cyclosporine Lovastatin Altocor® Increased lovastatin exposure and an increased risk of myopathy and rhabdomyolysis Details Cyclosporine Meclofenamate Meclodium® An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Mefenamic Acid Ponstel® An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Meloxicam Alloxate An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Meloxicam Injection Alloxate An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Melphalan Alkeran An increased risk of severe renal failure Details Cyclosporine Melphalan Injection Alkeran An increased risk of severe renal failure Details Cyclosporine Mercaptopurine Purinethol® Reduced cycloSPORINE exposure and an increased risk of hepatotoxicity Details Cyclosporine Methotrexate Jylamvo Increased methotrexate exposure, potentiation of methotrexate efficacy, methotrexate toxicity or methotrexate-related severe adver... Details Cyclosporine Methotrexate Injection Abitrexate® Increased methotrexate exposure, potentiation of methotrexate efficacy, methotrexate toxicity or methotrexate-related severe adver... Details Cyclosporine Methylergonovine Methergine Increased methylergonovine exposure Details Cyclosporine Metoclopramide Injection Gimoti Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Metoclopramide Nasal Spray Gimoti Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Mitapivat Aqvesme Increased P-gp substrate exposure; reduced CYP3A substrate exposure Details