Cyclosporine

Major

Cyclosporine Moexipril Univasc® Acute renal dysfunction and an increased risk of hyperkalemia Details Cyclosporine Morphine Injection Astramorph® PF Increased morphine exposure and an increased risk of morphine-related adverse effects (hypotension, respiratory depression, profou... Details Cyclosporine Nabumetone Relafen An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Nafcillin Injection Unipen® Injection Reduced cycloSPORINE exposure Details Cyclosporine Naproxen Aleve An increased risk of cycloSPORINE nephrotoxicity Details Cyclosporine Neratinib Nerlynx Increased neratinib exposure, an increased risk of neratinib toxicity and an increased cycloSPORINE exposure Details Cyclosporine Nevirapine Viramune Reduced cycloSPORINE exposure Details Cyclosporine Nicardipine Cardene Increased cycloSPORINE exposure Details Cyclosporine Nifedipine Adalat® Increased NIFEdipine exposure, increased cycloSPORINE exposure and an increased risk of gingival hyperplasia Details Cyclosporine Obeticholic Acid Ocaliva Increased risk of liver dysfunction Details Cyclosporine Octreotide Bynfezia Reduced cycloSPORINE exposure and reduced efficacy of cycloSPORINE Details Cyclosporine Octreotide Injection Bynfezia Reduced cycloSPORINE exposure and reduced efficacy of cycloSPORINE Details Cyclosporine Olaparib Lynparza Increased olaparib exposure Details Cyclosporine Orlistat Alli Reduced cycloSPORINE exposure Details Cyclosporine Perindopril Aceon Acute renal dysfunction and an increased risk of hyperkalemia Details

Moderate

Cyclosporine Clindamycin ANTIROBE Explained Decreased cycloSPORINE bioavailability Details Cyclosporine Omeprazole Gastrobim Explained Altered cycloSPORINE concentrations and increased omeprazole exposure Details Cyclosporine Trospium / Xanomeline Cobenfy Explained Increased oral sensitive CYP3A4 substrate that are P-gp substrates with NTI exposure and an increased risk on severity and frequen... Details Cyclosporine Abemaciclib Verzenio Explained Increased abemaciclib plasma concentration Details Cyclosporine Acetazolamide Diamox® Sequels® An increased risk of cycloSPORINE toxicity Details Cyclosporine Allopurinol Aloprim Increased cycloSPORINE exposure Details Cyclosporine Allopurinol Injection Aloprim Increased cycloSPORINE exposure Details Cyclosporine Amikacin Injection Amikin® Renal dysfunction or nephrotoxicity Details Cyclosporine Amikacin Oral Inhalation Arikayce Renal dysfunction or nephrotoxicity Details Cyclosporine Alfuzosin UroXatral An increase in alfuzosin exposure Details Cyclosporine Avanafil Stendra Increased avanafil exposure Details Cyclosporine Ceftriaxone Injection Rocephin® An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Chloramphenicol Injection Chloromycetin® Injection An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Chloroquine Aralen® An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Clindamycin Injection ANTIROBE Decreased cycloSPORINE bioavailability Details Cyclosporine Clindamycin Topical C/T/S® Decreased cycloSPORINE bioavailability Details Cyclosporine Clindamycin Vaginal Cleocin Decreased cycloSPORINE bioavailability Details Cyclosporine Clonidine Transdermal Patch Catapres An increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Colesevelam Welchol Decreased cycloSPORINE exposure and plasma concentrations Details Cyclosporine Danazol Danocrine® Increased cycloSPORINE exposure and an increased risk of cycloSPORINE toxicity (renal dysfunction, cholestasis, paresthesias) Details Cyclosporine Docetaxel Beizray An increased risk of docetaxel toxicity (anemia, leukopenia, thrombocytopenia, fever, diarrhea) Details Cyclosporine Docetaxel Injection Beizray An increased risk of docetaxel toxicity (anemia, leukopenia, thrombocytopenia, fever, diarrhea) Details Cyclosporine Dofetilide Tikosyn Increased dofetilide exposure Details Cyclosporine Famotidine Calmicid Decreased cycloSPORINE concentrations Details Cyclosporine Famotidine Injection Calmicid Decreased cycloSPORINE concentrations Details