Bromocriptine

16 interactions 1 explained in plain English
Also sold as: Cycloset Cycloset® Parlodel Parlodel®
About Bromocriptine

Bromocriptine (Parlodel) is used to treat symptoms of hyperprolactinemia (high levels of a natural substance called prolactin in the body) including lack of menstrual periods, discharge from the nipples, infertility (difficulty becoming pregnant) and hypogonadism (low levels of certain natural substances needed for nor… Read the full Bromocriptine drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Dihydroergotamine Injection Dihydroergotamine Nasal Spray Ketoconazole Topical Letermovir Injection Abametapir Cyclosporine Injection
4 Contraindicated 9 Major 3 Moderate
All (16) Contraindicated (4) Major (9) Moderate (3)

Contraindicated

Bromocriptine Dihydroergotamine Injection DHE-45® Injection An increased risk of ergotism Details Bromocriptine Dihydroergotamine Nasal Spray Migranal An increased risk of ergotism Details Bromocriptine Ketoconazole Topical Extina® Foam Increased ergot derivatives exposure and an increased risk of ergotism (nausea, vomiting, vasospastic ischemia) Details Bromocriptine Letermovir Injection Prevymis Increased ergot alkaloids exposure and an increased risk of ergotism Details

Major

Bromocriptine Abametapir Explained Increased exposure of CYP3A4 substrate Details Bromocriptine Cyclosporine Injection Atopica Increased cycloSPORINE exposure Details Bromocriptine Cyclosporine Ophthalmic Cequa Increased cycloSPORINE exposure Details Bromocriptine Furosemide Injection Disal An increased risk of hyperglycemia and an increased insulin requirement Details Bromocriptine Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Bromocriptine Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details Bromocriptine Insulin Glulisine (Rdna Origin) Injection Apidra An increased risk of hypoglycemia Details Bromocriptine Metoclopramide Injection Gimoti Diminished effectiveness of metoclopramide and the dopaminergic agent Details Bromocriptine Metoclopramide Nasal Spray Gimoti Diminished effectiveness of metoclopramide and the dopaminergic agent Details

Moderate

Bromocriptine Lanreotide Injection Somatuline Increased plasma levels of bromocriptine Details Bromocriptine Octreotide Bynfezia Increased bromocriptine exposure Details Bromocriptine Octreotide Injection Bynfezia Increased bromocriptine exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.