Dexamethasone Injection

308 interactions 1,214 cited references
Also sold as: Decadron Dexasone Dexium Dextenza Dexycu Hemady Maxidex Ozurdex
About Dexamethasone Injection

Dexamethasone injection is used to treat severe allergic reactions. It is used in the management of certain types of edema (fluid retention and swelling; excess fluid held in body tissues,) gastrointestinal disease, and certain types of arthritis. Dexamethasone injection is also used for diagnostic testing. Dexamethaso… Read the full Dexamethasone Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Dexamethasone Injection Abametapir Increased exposure of CYP3A4 substrate Details Dexamethasone Injection Aceclofenac Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Injection Acemetacin Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Injection Aldesleukin Proleukin Reduced antitumor effectiveness Details Dexamethasone Injection Alfentanil Reduced ALfentanil exposure, reduced efficacy of ALfentanil and an increased risk of a withdrawal syndrome Details Dexamethasone Injection Amiodarone Nexterone Reduced amiodarone exposure and reduced efficacy of amiodarone Details Dexamethasone Injection Amlodipine Amvaz® Reduced amLODIPine exposure Details Dexamethasone Injection Amtolmetin Guacil Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Injection Apalutamide Erleada Reduced dexAMETHasone exposure Details Dexamethasone Injection Artemether Reduced artemether/lumefantrine exposure, reduced efficacy of artemether/lumefantrine, loss of antimalarial efficacy, reduced CYP3... Details Dexamethasone Injection Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Dexamethasone Injection Atazanavir Reyataz Reduced atazanavir exposure, reduced efficacy of atazanavir, increased dexAMETHasone exposure and increased risk of dexAMETHasone-... Details Dexamethasone Injection Atogepant Qulipta Reduced atogepant exposure Details Dexamethasone Injection Avacopan Tavneos Increased CYP3A4 substrate exposure Details Dexamethasone Injection Balofloxacin An increased risk of tendon rupture Details Dexamethasone Injection Bemiparin Increased risk of bleeding Details Dexamethasone Injection Benzhydrocodone Reduced HYDROcodone exposure and reduced efficacy HYDROcodone Details Dexamethasone Injection Besifloxacin An increased risk of tendon rupture Details Dexamethasone Injection Boceprevir Reduced boceprevir plasma concentrations and increased dexamethasone plasma concentrations Details Dexamethasone Injection Bromfenac Bromsite Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Injection Bufexamac Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Injection Buprenorphine Belbuca Reduced buprenorphine exposure and reduced efficacy of buprenorphine Details Dexamethasone Injection Bupropion Aplenzin Lowering of the seizure threshold Details Dexamethasone Injection Carbamazepine Carbatrol Reduced dexAMETHasone exposure and reduced carBAMazepine exposure Details Dexamethasone Injection Cariprazine Vraylar Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Dexamethasone Injection Celecoxib Celebrex Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Injection Ceritinib Zykadia Increased CYP3A substrate exposure Details Dexamethasone Injection Cholestyramine Prevalite Decreased dexamethasone concentration Details Dexamethasone Injection Choline Salicylate Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Injection Ciprofloxacin An increased risk of tendon rupture Details Dexamethasone Injection Clarithromycin Biaxin Reduced CYP3A substrate exposure and increased dexAMETHasone exposure Details Dexamethasone Injection Clonixin Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Injection Cobicistat Tybost Reduced cobicistat exposure and increased dexAMETHasone exposure Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.