Aripiprazole Lauroxil

75 interactions 5 explained in plain English

Also sold as: Aristada

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Metoclopramide Nasal Spray Metoclopramide Injection Ketoconazole Topical Morphine Injection Galantamine Oxaliplatin Injection

3 Contraindicated 71 Major 1 Moderate

All (75) Contraindicated (3) Major (71) Moderate (1)

Contraindicated

Aripiprazole Lauroxil Ketoconazole Topical Extina® Foam Increased ARIPiprazole exposure and an increased risk of QT interval prolongation Details Aripiprazole Lauroxil Metoclopramide Injection Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details Aripiprazole Lauroxil Metoclopramide Nasal Spray Gimoti An increased risk of extrapyramidal reactions and neuroleptic malignant syndrome Details

Major

Aripiprazole Lauroxil Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of respiratory and CNS depression Details Aripiprazole Lauroxil Amitriptyline Elavil Explained An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Sertraline Explained Increased risk of QT interval prolongation and an increased CYP2D6 substrate exposure Details Aripiprazole Lauroxil Buprenorphine Belbuca Explained An increased risk of QT interval prolongation and an increased risk of CNS and respiratory depression Details Aripiprazole Lauroxil Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Aripiprazole Lauroxil Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Aripiprazole Lauroxil Arsenic Trioxide Trisenox An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Arsenic Trioxide Injection Trisenox An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Asenapine Transdermal Patch Secuado An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Azithromycin AzaSite An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Cabergoline Dostinex® Reduced efficacy of cabergoline and reduced efficacy of dopamine-2 receptors Details Aripiprazole Lauroxil Alfuzosin UroXatral An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Anagrelide Agrylin An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Bedaquiline Sirturo An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Chloroquine Aralen® An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Dacomitinib Vizimpro Increased ARIPiprazole exposure Details Aripiprazole Lauroxil Dasatinib Phyrago An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Aripiprazole Lauroxil Diazepam Nasal Spray Valtoco Increased risk of CNS depression and orthostatic hypotension Details Aripiprazole Lauroxil Diazepam Rectal Diastat Increased risk of CNS depression and orthostatic hypotension Details Aripiprazole Lauroxil Disopyramide Norpace An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Dofetilide Tikosyn An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Dolasetron Anzemet An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Dolasetron Injection Anzemet An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Encorafenib Braftovi Reduced ARIPiprazole or ARIPiprazole lauroxil (prodrug of ARIPiprazole) exposure and an increased risk of QT interval prolongation Details Aripiprazole Lauroxil Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Eribulin Injection Halaven An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Famotidine Calmicid An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Famotidine Injection Calmicid An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Felbamate Felbatol An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Fentanyl Transdermal Patch Duragesic® Increased risk of profound sedation, respiratory depression, hypotension, coma and death Details Aripiprazole Lauroxil Flecainide Tambocor® An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Foscarnet Injection Foscavir An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Fostemsavir Rukobia Increased risk of torsade de pointes Details Aripiprazole Lauroxil Galantamine Razadyne An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Gatifloxacin Ophthalmic Zymar® An increased risk of QT interval prolongation Details Aripiprazole Lauroxil Gemifloxacin Factive An increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.