Dexamethasone Ophthalmic

308 interactions 1,214 cited references
Also sold as: Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Dexair Dexasporin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Maxidex® Maxitrol® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Neodecadron® (as a combination product containing Dexamethasone, Neomycin) TobraDex® (as a combination product containing Dexamethasone, Tobramycin)
About Dexamethasone Ophthalmic

Dexamethasone reduces the irritation, redness, burning, and swelling of eye caused by chemicals, heat, radiation, infection, allergy, or foreign bodies in the eye. It is sometimes used after eye surgery. Read the full Dexamethasone Ophthalmic drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Dexamethasone Ophthalmic Abametapir Increased exposure of CYP3A4 substrate Details Dexamethasone Ophthalmic Aceclofenac Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Ophthalmic Acemetacin Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Ophthalmic Aldesleukin Proleukin Reduced antitumor effectiveness Details Dexamethasone Ophthalmic Alfentanil Reduced ALfentanil exposure, reduced efficacy of ALfentanil and an increased risk of a withdrawal syndrome Details Dexamethasone Ophthalmic Amiodarone Nexterone Reduced amiodarone exposure and reduced efficacy of amiodarone Details Dexamethasone Ophthalmic Amlodipine Amvaz® Reduced amLODIPine exposure Details Dexamethasone Ophthalmic Amtolmetin Guacil Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Ophthalmic Apalutamide Erleada Reduced dexAMETHasone exposure Details Dexamethasone Ophthalmic Artemether Reduced artemether/lumefantrine exposure, reduced efficacy of artemether/lumefantrine, loss of antimalarial efficacy, reduced CYP3... Details Dexamethasone Ophthalmic Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Dexamethasone Ophthalmic Atazanavir Reyataz Reduced atazanavir exposure, reduced efficacy of atazanavir, increased dexAMETHasone exposure and increased risk of dexAMETHasone-... Details Dexamethasone Ophthalmic Atogepant Qulipta Reduced atogepant exposure Details Dexamethasone Ophthalmic Avacopan Tavneos Increased CYP3A4 substrate exposure Details Dexamethasone Ophthalmic Balofloxacin An increased risk of tendon rupture Details Dexamethasone Ophthalmic Bemiparin Increased risk of bleeding Details Dexamethasone Ophthalmic Benzhydrocodone Reduced HYDROcodone exposure and reduced efficacy HYDROcodone Details Dexamethasone Ophthalmic Besifloxacin An increased risk of tendon rupture Details Dexamethasone Ophthalmic Boceprevir Reduced boceprevir plasma concentrations and increased dexamethasone plasma concentrations Details Dexamethasone Ophthalmic Bromfenac Bromsite Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Ophthalmic Bufexamac Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Ophthalmic Buprenorphine Belbuca Reduced buprenorphine exposure and reduced efficacy of buprenorphine Details Dexamethasone Ophthalmic Bupropion Aplenzin Lowering of the seizure threshold Details Dexamethasone Ophthalmic Carbamazepine Carbatrol Reduced dexAMETHasone exposure and reduced carBAMazepine exposure Details Dexamethasone Ophthalmic Cariprazine Vraylar Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Dexamethasone Ophthalmic Celecoxib Celebrex Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Ophthalmic Ceritinib Zykadia Increased CYP3A substrate exposure Details Dexamethasone Ophthalmic Cholestyramine Prevalite Decreased dexamethasone concentration Details Dexamethasone Ophthalmic Choline Salicylate Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Ophthalmic Ciprofloxacin An increased risk of tendon rupture Details Dexamethasone Ophthalmic Clarithromycin Biaxin Reduced CYP3A substrate exposure and increased dexAMETHasone exposure Details Dexamethasone Ophthalmic Clonixin Increased risk of gastrointestinal ulcer or bleeding Details Dexamethasone Ophthalmic Cobicistat Tybost Reduced cobicistat exposure and increased dexAMETHasone exposure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.