Gemcitabine

30 interactions 659 cited references
Also sold as: Avgemsi Infugem Inlexzo

Read the full Gemcitabine drug information page

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Measles Virus Vaccine, Live Smallpox Monkeypox Vaccine Bacillus Of Calmette And Guerin Vaccine, Live Rubella Virus Vaccine, Live Mumps Virus Vaccine, Live Dengue Tetravalent Vaccine, Live
9 Contraindicated 15 Major 6 Minor
All (30) Contraindicated (9) Major (15) Minor (6)

Contraindicated

Gemcitabine Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Gemcitabine Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Gemcitabine Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Gemcitabine Azathioprine Azasan An increased risk of hepatotoxicity Details Gemcitabine Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Gemcitabine Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Gemcitabine Cedazuridine Increased exposure of cytidine deaminase substrates and increased risk of toxicity Details Gemcitabine Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Gemcitabine Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Hexaminolevulinate Increased risk of false positive cytoscopy results Details Gemcitabine Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Islatravir Reduced islatravir-triphosphate exposure and reduced efficacy of islatravir Details Gemcitabine Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Gemcitabine Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Gemcitabine Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Gemcitabine Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details Gemcitabine Warfarin Coumadin An increased risk of bleeding Details Gemcitabine Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details

Minor

Gemcitabine Capecitabine Xeloda Enhanced fluorouracil systemic exposure and possible toxicity Details Gemcitabine Fluorouracil Adrucil Enhanced fluorouracil systemic exposure and possible toxicity Details Gemcitabine Fluorouracil Injection Adrucil Enhanced fluorouracil systemic exposure and possible toxicity Details Gemcitabine Fluorouracil Topical Carac Enhanced fluorouracil systemic exposure and possible toxicity Details Gemcitabine Doxifluridine Enhanced fluorouracil systemic exposure and possible toxicity Details Gemcitabine Tegafur Enhanced fluorouracil systemic exposure and possible toxicity Details

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