Ertugliflozin

89 interactions 159 cited references

Also sold as: Steglatro Steglatro®

About Ertugliflozin

Ertugliflozin is used along with diet and exercise, and sometimes with other medications, to lower blood sugar levels in people with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Ertugliflozin is in a class of medications called sodium-glucose co… Read the full Ertugliflozin drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Abiraterone Gatifloxacin Ophthalmic Insulin Detemir (Rdna Origin) Injection Ofloxacin Otic Octreotide Injection Meloxicam Injection

51 Major 38 Moderate

All (89) Major (51) Moderate (38)

Major

Ertugliflozin Abiraterone Abirtega An increased risk of severe hypoglycemia Details Ertugliflozin Delafloxacin Baxdela Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Delafloxacin Injection Baxdela Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Abiraterone Acetate Abirtega An increased risk of severe hypoglycemia Details Ertugliflozin Abiraterone Acetate, Micronized Abirtega An increased risk of severe hypoglycemia Details Ertugliflozin Cannabidiol Epidiolex Increased UGT1A9 substrate exposure and an increased risk of UGT1A9 substrate-related adverse reactions Details Ertugliflozin Ciprofloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Enoxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Gatifloxacin Zymaxid Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Gemifloxacin Factive Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Grepafloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Hydroxychloroquine Plaquenil Enhanced hypoglycemic effect of antidiabetics and an increased risk of hypoglycemia Details Ertugliflozin Insulin Afrezza An increased risk of hypoglycemia Details Ertugliflozin Insulin Aspart, Recombinant Fiasp An increased risk of hypoglycemia Details Ertugliflozin Insulin Bovine An increased risk of hypoglycemia Details Ertugliflozin Insulin Degludec Tresiba An increased risk of hypoglycemia Details Ertugliflozin Insulin Detemir Levemir An increased risk of hypoglycemia Details Ertugliflozin Insulin Glargine, Recombinant Basaglar An increased risk of hypoglycemia Details Ertugliflozin Insulin Glulisine Apidra An increased risk of hypoglycemia Details Ertugliflozin Insulin Icodec-Abae Awiqli An increased risk of hypoglycemia Details Ertugliflozin Insulin Lispro, Recombinant Admelog An increased risk of hypoglycemia Details Ertugliflozin Lanreotide Acetate An increased risk of hypoglycemia and impaired glucose regulation Details Ertugliflozin Levofloxacin Levaquin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Lithium Reduced lithium exposure Details Ertugliflozin Lomefloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Meloxicam Alloxate Increased meloxicam exposure and reduced meloxicam metabolic clearance Details Ertugliflozin Moxifloxacin Avelox Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Norfloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Octreotide Acetate An increased risk of hypoglycemia and impaired glucose regulation Details Ertugliflozin Ofloxacin Floxin® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Pasireotide Diaspartate An increased risk of hypoglycemia and impaired glucose regulation Details Ertugliflozin Pramlintide Symlin An increased risk of hypoglycemia Details Ertugliflozin Somatrogon-Ghla Reduced insulin sensitivity Details Ertugliflozin Sparfloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Thioctic Acid Increased risk of hypoglycemia Details Ertugliflozin Trovafloxacin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Voriconazole Vfend Increased voriconazole exposure Details Ertugliflozin Gatifloxacin Ophthalmic Zymar® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Ertugliflozin Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) An increased risk of hypoglycemia Details Ertugliflozin Insulin Detemir (Rdna Origin) Injection Levemir An increased risk of hypoglycemia Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.