Dacarbazine

17 interactions 393 cited references
Also sold as: DTIC-Dome®
About Dacarbazine

Dacarbazine is used to treat melanoma (a type of skin cancer) that has spread to other parts of your body. Dacarbazine is also used in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease; a type of cancer that begins in a type of white blood cells that normally fights infection). Dacarbazi… Read the full Dacarbazine drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Measles Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Mumps Virus Vaccine, Live Varicella Virus Vaccine, Live
9 Contraindicated 7 Major 1 Moderate
All (17) Contraindicated (9) Major (7) Moderate (1)

Contraindicated

Dacarbazine Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Dacarbazine Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Dacarbazine Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Dacarbazine Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Dacarbazine Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Dacarbazine Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Dacarbazine Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Pexidartinib Turalio Hepatotoxicity Details Dacarbazine Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

Moderate

Dacarbazine Aldesleukin Proleukin In increased risk for hypersensitivity reactions (erythema, pruritus, hypotension) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.