Dacarbazine

Name: Dacarbazine Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

17 interactions 393 cited references

Also sold as: DTIC-Dome®

About Dacarbazine

Dacarbazine is used to treat melanoma (a type of skin cancer) that has spread to other parts of your body. Dacarbazine is also used in combination with other medications to treat Hodgkin's lymphoma (Hodgkin's disease; a type of cancer that begins in a type of white blood cells that normally fights infection). Dacarbazi… Read the full Dacarbazine drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Typhoid Vaccine Measles Virus Vaccine, Live Rubella Virus Vaccine, Live Smallpox Monkeypox Vaccine Mumps Virus Vaccine, Live Varicella Virus Vaccine, Live

9 Contraindicated 7 Major 1 Moderate

All (17) Contraindicated (9) Major (7) Moderate (1)

Major

Dacarbazine Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Dacarbazine Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Dacarbazine Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Dacarbazine Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Dacarbazine Pexidartinib Turalio Hepatotoxicity Details Dacarbazine Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.