Pivampicillin

15 interactions
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Demeclocycline Doxycycline Injection Eravacycline Injection Hydroxychloroquine Levonorgestrel Levonorgestrel Intrauterine System
10 Major 5 Minor
All (15) Major (10) Minor (5)

Major

Pivampicillin Demeclocycline Declomycin® Decreased antibacterial effectiveness Details Pivampicillin Doxycycline Injection Acticlate Decreased antibacterial effectiveness Details Pivampicillin Eravacycline Injection Xerava Decreased antibacterial effectiveness Details Pivampicillin Hydroxychloroquine Plaquenil An increased risk of seizures Details Pivampicillin Levonorgestrel After banger Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Pivampicillin Levonorgestrel Intrauterine System Kyleena Reduced levonorgestrel exposure, reduced efficacy of levonorgestrel and an increased risk of breakthrough bleeding and/or contrace... Details Pivampicillin Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Pivampicillin Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Pivampicillin Minocycline Amzeeq Decreased antibacterial effectiveness Details Pivampicillin Minocycline Topical Amzeeq Decreased antibacterial effectiveness Details

Minor

Pivampicillin Amikacin Injection Amikin® Loss of aminoglycoside efficacy Details Pivampicillin Amikacin Oral Inhalation Arikayce Loss of aminoglycoside efficacy Details Pivampicillin Gentamicin Injection Garamycin® I.V. Loss of aminoglycoside efficacy Details Pivampicillin Gentamicin Ophthalmic Garamycin® Ophthalmic Loss of aminoglycoside efficacy Details Pivampicillin Gentamicin Topical Garamycin® Loss of aminoglycoside efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.