Lurbinectedin
7 interactions 1 explained in plain English
Also sold as:
Zepzelca
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Abametapir
Encorafenib
Ketoconazole Topical
Lefamulin
Lenacapavir Injection
Lenacapavir Oral
Major
Lurbinectedin Abametapir Explained Increased exposure of CYP3A4 substrate Details Lurbinectedin Encorafenib Braftovi Reduced lurbinectedin exposure and reduced efficacy of lurbinectedin Details Lurbinectedin Ketoconazole Topical Extina® Foam Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Lurbinectedin Lefamulin Xenleta Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Lurbinectedin Lenacapavir Injection Sunlenca Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Lurbinectedin Lenacapavir Oral Sunlenca Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions Details Lurbinectedin Letermovir Injection Prevymis Increased lurbinectedin exposure and an increased risk of lurbinectedin-related adverse reactions DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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