Ado-Trastuzumab Emtansine Injection

35 interactions 142 cited references

Also sold as: KADCYLA Kadcyla®

About Ado-Trastuzumab Emtansine Injection

Ado-trastuzumab emtansine injection is used to treat a certain type of breast cancer that has spread to other parts of the body and has not improved or has worsened after treatment with other medications. Ado-trastuzumab emtansine is also used after surgery for a certain type of breast cancer in women who have had trea… Read the full Ado-Trastuzumab Emtansine Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Yellow Fever Vaccine Smallpox Monkeypox Vaccine Rubella Virus Vaccine, Live Bacillus Of Calmette And Guerin Vaccine, Live Mumps Virus Vaccine, Live Measles Virus Vaccine, Live

9 Contraindicated 26 Major

All (35) Contraindicated (9) Major (26)

Contraindicated

Ado-Trastuzumab Emtansine Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Ado-Trastuzumab Emtansine Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Atazanavir Reyataz Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Boceprevir Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Clarithromycin Biaxin Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Cobicistat Tybost Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Conivaptan Vaprisol Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Idelalisib Zydelig Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Indinavir Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Itraconazole Sporanox Increased cytotoxic component DM1 (maytansine derivative) exposure and an increased risk of toxicity Details Ado-Trastuzumab Emtansine Injection Ketoconazole Extina Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Lopinavir Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Nefazodone Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Nelfinavir Viracept Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Posaconazole Noxafil Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Ribociclib Kisqali Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Ritonavir Norvir Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details Ado-Trastuzumab Emtansine Injection Saquinavir Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Telaprevir Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Telithromycin Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Tipranavir Aptivus Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details Ado-Trastuzumab Emtansine Injection Voriconazole Vfend Increased exposure of cytotoxic component DM1 (maytansine derivative) and risk of toxicity Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.