Moclobemide

16 interactions 2 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Deutetrabenazine Levodopa Oral Inhalation Diethylpropion Amitriptyline Acetaminophen And Codeine Metoclopramide Injection
5 Contraindicated 10 Major 1 Moderate
All (16) Contraindicated (5) Major (10) Moderate (1)

Contraindicated

Moclobemide Acetaminophen And Codeine Capital® & Codeine Explained Increased risk of serotonin syndrome, increased codeine exposure and reduced active metabolite (morphine) exposure Details Moclobemide Amitriptyline Elavil Explained Neurotoxicity, seizures, or serotonin syndrome (hypertension, hyperthermia, myoclonus, mental status changes) Details Moclobemide Deutetrabenazine Austedo Hypertensive crisis (headache, hyperpyrexia, hypertension) Details Moclobemide Diethylpropion Tenuate Hypertensive crisis (headache, hyperpyrexia, hypertension) Details Moclobemide Levodopa Oral Inhalation Inbrija Hypertensive crisis Details

Major

Moclobemide Atropine Ophthalmic Atropine Care 1% Potential to cause hypertensive crisis Details Moclobemide Brexpiprazole Rexulti Increased brexpiprazole exposure Details Moclobemide Dolasetron Anzemet Increased risk of serotonin syndrome Details Moclobemide Dolasetron Injection Anzemet Increased risk of serotonin syndrome Details Moclobemide Granisetron Transdermal Patch Sancuso Increased risk of serotonin syndrome Details Moclobemide Granisetron Injection Granisol Increased risk of serotonin syndrome Details Moclobemide Lithium Carbonate Lithobid Increased risk of serotonin syndrome Details Moclobemide Metoclopramide Injection Gimoti Increased risk of hypertensive crisis Details Moclobemide Metoclopramide Nasal Spray Gimoti Increased risk of hypertensive crisis Details Moclobemide Nebivolol Bystolic Increased exposure to nebivolol Details

Moderate

Moclobemide Clopidogrel Plavix Reduced clopidogrel active metabolite exposure and reduced platelet inhibition Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.