Diflorasone Topical

29 interactions 153 cited references
Also sold as: Apexicon Florone® Psorcon Psorcon®
About Diflorasone Topical

Diflorasone is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body and eczema (a skin disease that causes the skin to be dry and itchy and to sometimes deve… Read the full Diflorasone Topical drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Mifepristone Desmopressin Upadacitinib Lutetium Lu 177 Dotatate Insulin Icodec-Abae Insulin Glargine, Recombinant
2 Contraindicated 18 Major 9 Moderate
All (29) Contraindicated (2) Major (18) Moderate (9)

Contraindicated

Diflorasone Topical Desmopressin DDAVP Increased risk of severe hyponatremia Details Diflorasone Topical Mifepristone Korlym An increased risk of autoimmune disorders and an increased risk of acute adrenal insufficiency, that may lead to exacerbation or d... Details

Major

Diflorasone Topical Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Diflorasone Topical Bemiparin Increased risk of bleeding Details Diflorasone Topical Carbamazepine Carbatrol Reduced corticosteroids exposure and reduced efficacy of corticosteroids Details Diflorasone Topical Cosyntropin False elevations of plasma cortisol levels Details Diflorasone Topical Ethinyl Estradiol Increased corticosteroid exposure Details Diflorasone Topical Fosphenytoin Cerebyx Reduced corticosteroid exposure Details Diflorasone Topical Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Diflorasone Topical Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Diflorasone Topical Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Diflorasone Topical Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Diflorasone Topical Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Diflorasone Topical Nadroparin Increased risk of bleeding Details Diflorasone Topical Phenytoin Dilantin Reduced corticosteroid exposure Details Diflorasone Topical Rabies Vaccine Imovax An inadequate immunological response to the vaccine, an increased risk of altered immunocompetence and reduced immune response to... Details Diflorasone Topical Relacorilant Lifyorli Reduced relacorilant exposure and reduced efficacy of relacorilant, reduced glucocorticoids exposure and reduced efficacy of gluco... Details Diflorasone Topical Sargramostim Leukine Increased myeloproliferative effects of sargramostim Details Diflorasone Topical Somatrogon-Ghla Reduced serum cortisol exposure, an increased risk of central (secondary) hypoadrenalism and attenuated growth-promoting effects o... Details Diflorasone Topical Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details

Moderate

Diflorasone Topical Auranofin Ridaura Increased risk of auranofin-related adverse effects Details Diflorasone Topical Gallium Ga 68 Dotatate Increased risk of false negative imaging Details Diflorasone Topical Indapamide An increased risk of hypokalemia Details Diflorasone Topical Insulin Afrezza Reduced blood glucose lowering effect of insulin Details Diflorasone Topical Insulin Lispro, Recombinant Admelog May decrease blood glucose lowering effect of insulin lispro Details Diflorasone Topical Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details Diflorasone Topical Olodaterol Striverdi An increased risk of hypokalemia Details Diflorasone Topical Rotavirus Vaccine, Live An inadequate immunological response to the vaccine Details Diflorasone Topical Testosterone Androderm Increased risk of edema Details

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