Ganaxolone

30 interactions 2 explained in plain English
Also sold as: Ztalmy
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Moderate

Ganaxolone Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of somnolence and sedation Details Ganaxolone Buprenorphine Belbuca Explained An increased risk of somnolence and sedation Details Ganaxolone Aripiprazole Injection Abilify An increased risk of somnolence and sedation Details Ganaxolone Asenapine Transdermal Patch Secuado An increased risk of somnolence and sedation Details Ganaxolone Butorphanol Injection Butorphic An increased risk of somnolence and sedation Details Ganaxolone Butorphanol Nasal Spray Stadol® NS An increased risk of somnolence and sedation Details Ganaxolone Cetirizine Injection Aller-Tec An increased risk of somnolence and sedation Details Ganaxolone Cetirizine Ophthalmic Zerviate An increased risk of somnolence and sedation Details Ganaxolone Diazepam Nasal Spray Valtoco An increased risk of somnolence and sedation Details Ganaxolone Diazepam Rectal Diastat An increased risk of somnolence and sedation Details Ganaxolone Diphenhydramine Injection Banophen An increased risk of somnolence and sedation Details Ganaxolone Diphenhydramine Topical Afterbite with Antihistamine An increased risk of somnolence and sedation Details Ganaxolone Esketamine Nasal Spray Spravato An increased risk of somnolence and sedation Details Ganaxolone Fentanyl Transdermal Patch Duragesic® An increased risk of somnolence and sedation Details Ganaxolone Folic Acid Folacin Reduced folic acid exposure and reduced efficacy of folic acid Details Ganaxolone Hydromorphone Injection Dilaudid An increased risk of somnolence and sedation Details Ganaxolone Hydromorphone Rectal available generically An increased risk of somnolence and sedation Details Ganaxolone Midazolam Nasal Spray Nayzilam An increased risk of somnolence and sedation Details Ganaxolone Midazolam Injection Nayzilam An increased risk of somnolence and sedation Details Ganaxolone Morphine Injection Astramorph® PF An increased risk of somnolence and sedation Details Ganaxolone Nalbuphine Injection Nubain® An increased risk of somnolence and sedation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.