Ganaxolone
30 interactions 2 explained in plain English
Also sold as:
Ztalmy
Medically reviewed by
Dr. Brian Staiger, PharmD, BCPS
· Updated Jul 4, 2026
· Editorial policy
· Data sources
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Most serious with:
Dexamethasone Injection
Dexamethasone Ophthalmic
Encorafenib
Hydroxychloroquine
Orlistat
Nafcillin Injection
Major
Ganaxolone Dexamethasone Injection Decadron Reduced ganaxolone exposure and reduced efficacy of ganaxolone Details Ganaxolone Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced ganaxolone exposure and reduced efficacy of ganaxolone Details Ganaxolone Encorafenib Braftovi Reduced ganaxolone exposure and reduced efficacy of ganaxolone Details Ganaxolone Hydroxychloroquine Plaquenil Impaired antiepileptic activity Details Ganaxolone Letermovir Injection Prevymis Increased CYP3A substrate exposure Details Ganaxolone Mefenamic Acid Ponstel® Increased ganaxolone exposure and an increased risk of ganaxolone-related adverse reactions Details Ganaxolone Mitapivat Aqvesme Reduced ganaxolone exposure and reduced efficacy of ganaxolone Details Ganaxolone Nafcillin Injection Unipen® Injection Reduced ganaxolone exposure and reduced efficacy of ganaxolone Details Ganaxolone Orlistat Alli Reduced efficacy of anticonvulsant DetailsModerate
Ganaxolone Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of somnolence and sedation Details Ganaxolone Buprenorphine Belbuca Explained An increased risk of somnolence and sedation Details Ganaxolone Aripiprazole Injection Abilify An increased risk of somnolence and sedation Details Ganaxolone Asenapine Transdermal Patch Secuado An increased risk of somnolence and sedation Details Ganaxolone Butorphanol Injection Butorphic An increased risk of somnolence and sedation Details Ganaxolone Butorphanol Nasal Spray Stadol® NS An increased risk of somnolence and sedation Details Ganaxolone Cetirizine Injection Aller-Tec An increased risk of somnolence and sedation Details Ganaxolone Cetirizine Ophthalmic Zerviate An increased risk of somnolence and sedation Details Ganaxolone Diazepam Nasal Spray Valtoco An increased risk of somnolence and sedation Details Ganaxolone Diazepam Rectal Diastat An increased risk of somnolence and sedation Details Ganaxolone Diphenhydramine Injection Banophen An increased risk of somnolence and sedation Details Ganaxolone Diphenhydramine Topical Afterbite with Antihistamine An increased risk of somnolence and sedation Details Ganaxolone Esketamine Nasal Spray Spravato An increased risk of somnolence and sedation Details Ganaxolone Fentanyl Transdermal Patch Duragesic® An increased risk of somnolence and sedation Details Ganaxolone Folic Acid Folacin Reduced folic acid exposure and reduced efficacy of folic acid Details Ganaxolone Hydromorphone Injection Dilaudid An increased risk of somnolence and sedation Details Ganaxolone Hydromorphone Rectal available generically An increased risk of somnolence and sedation Details Ganaxolone Midazolam Nasal Spray Nayzilam An increased risk of somnolence and sedation Details Ganaxolone Midazolam Injection Nayzilam An increased risk of somnolence and sedation Details Ganaxolone Morphine Injection Astramorph® PF An increased risk of somnolence and sedation Details Ganaxolone Nalbuphine Injection Nubain® An increased risk of somnolence and sedation DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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