Delafloxacin Injection

45 interactions 27 cited references

Also sold as: Baxdela Baxdela®

About Delafloxacin Injection

Delafloxacin injection is used treat skin infections and certain types of pneumonia (an infection of the lungs) caused by bacteria in adults. Delafloxacin is in a class of antibiotics called fluoroquinolones. It works by killing the bacteria that cause infections. Read the full Delafloxacin Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acarbose Albiglutide Alogliptin Canagliflozin Chlorpropamide Ciprofloxacin

39 Major 6 Moderate

All (45) Major (39) Moderate (6)

Major

Delafloxacin Injection Acarbose Prandase® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Albiglutide Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Alogliptin Nesina Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Canagliflozin Invokana Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Chlorpropamide Diabinese® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Ciprofloxacin An increased risk of fluoroquinolones-related adverse reactions and an increased risk of seizures Details Delafloxacin Injection Dapagliflozin Farxiga Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Dulaglutide Trulicity Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Empagliflozin Glyxambi® (as a combination product containing Empagliflozin and Linagliptin) Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Ertugliflozin Steglatro Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Exenatide Bydureon Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Glimepiride Amaryl Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Glipizide Glucotrol Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Glyburide DiaBeta® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Insulin Afrezza Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Insulin Aspart, Recombinant Fiasp Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Insulin Bovine Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Insulin Degludec Tresiba Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Insulin Detemir Levemir Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Insulin Glulisine Apidra Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Insulin Lispro, Recombinant Admelog Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Linagliptin Tradjenta Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Liraglutide Saxenda Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Lixisenatide Changes in blood glucose with an increased risk of hypoglycemia or hyperglycemia and delayed therapeutic effect of antibiotic Details Delafloxacin Injection Magnesium Sulfate May reduce absorption of fluoroquinolone antibiotics Details Delafloxacin Injection Metformin Fortamet® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Miglitol Glyset® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Nateglinide Starlix® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Pioglitazone Actos Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Porfimer Excessive intracellular damage in photosensitized tissues Details Delafloxacin Injection Pramlintide Symlin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Repaglinide Prandin® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Rosiglitazone Avandia® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Saxagliptin Onglyza Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Semaglutide Ozempic Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Sitagliptin Brynovin Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Tolazamide Tolinase® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Tolbutamide Orinase® Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details Delafloxacin Injection Voglibose Changes in blood glucose and increased risk of hypoglycemia or hyperglycemia Details

Moderate

Delafloxacin Injection Aluminum Decreased delafloxacin efficacy Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.