Fluocinonide Topical

27 interactions 201 cited references
Also sold as: Dermacin® Fluex® Fluonex® Licon® Lidex-E® Lidex® Vanos®
About Fluocinonide Topical

Fluocinonide topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body and eczema (a skin disease that causes the skin to be dry and itchy and to somet… Read the full Fluocinonide Topical drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Fluocinonide Topical Aspirin Acuprin® An increased risk of salicylism subsequent to withdrawal of corticosteroids Details Fluocinonide Topical Bemiparin Increased risk of bleeding Details Fluocinonide Topical Carbamazepine Carbatrol Reduced corticosteroids exposure and reduced efficacy of corticosteroids Details Fluocinonide Topical Cosyntropin False elevations of plasma cortisol levels Details Fluocinonide Topical Ethinyl Estradiol Increased corticosteroid exposure Details Fluocinonide Topical Fosphenytoin Cerebyx Reduced corticosteroid exposure Details Fluocinonide Topical Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Fluocinonide Topical Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Fluocinonide Topical Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Fluocinonide Topical Lutetium Lu 177 Dotatate Decreased lutetium Lu 177 dotatate efficacy Details Fluocinonide Topical Macimorelin False-positive or false-negative adult growth hormone deficiency diagnosis Details Fluocinonide Topical Nadroparin Increased risk of bleeding Details Fluocinonide Topical Phenytoin Dilantin Reduced corticosteroid exposure Details Fluocinonide Topical Relacorilant Lifyorli Reduced relacorilant exposure and reduced efficacy of relacorilant, reduced glucocorticoids exposure and reduced efficacy of gluco... Details Fluocinonide Topical Sargramostim Leukine Increased myeloproliferative effects of sargramostim Details Fluocinonide Topical Somatrogon-Ghla Reduced serum cortisol exposure, an increased risk of central (secondary) hypoadrenalism and attenuated growth-promoting effects o... Details Fluocinonide Topical Upadacitinib Rinvoq Increased risk of gastrointestinal perforations Details

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