Fluocinonide Topical

Name: Fluocinonide Topical Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

27 interactions 201 cited references

Also sold as: Dermacin® Fluex® Fluonex® Licon® Lidex-E® Lidex® Vanos®

About Fluocinonide Topical

Fluocinonide topical is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions, including psoriasis (a skin disease in which red, scaly patches form on some areas of the body and eczema (a skin disease that causes the skin to be dry and itchy and to somet… Read the full Fluocinonide Topical drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Desmopressin Mifepristone Aspirin Bemiparin Carbamazepine Cosyntropin

2 Contraindicated 17 Major 8 Moderate

All (27) Contraindicated (2) Major (17) Moderate (8)

Moderate

Fluocinonide Topical Gallium Ga 68 Dotatate Increased risk of false negative imaging Details Fluocinonide Topical Indapamide An increased risk of hypokalemia Details Fluocinonide Topical Insulin Afrezza Reduced blood glucose lowering effect of insulin Details Fluocinonide Topical Insulin Lispro, Recombinant Admelog May decrease blood glucose lowering effect of insulin lispro Details Fluocinonide Topical Metformin Fortamet® An increased risk of hyperglycemia and potential loss of glycemic control Details Fluocinonide Topical Olodaterol Striverdi An increased risk of hypokalemia Details Fluocinonide Topical Rotavirus Vaccine, Live An inadequate immunological response to the vaccine Details Fluocinonide Topical Testosterone Androderm Increased risk of edema Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.