Rufinamide
20 interactions 1 explained in plain EnglishRufinamide is used with other medication(s) to control seizures in people who have Lennox-Gastaut syndrome (a severe form of epilepsy that begins during childhood and causes several types of seizures, behavioral disturbances, and developmental delays). Rufinamide is in a class of medications called anticonvulsants. It… Read the full Rufinamide drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Major
Rufinamide Atogepant Qulipta Reduced atogepant exposure Details Rufinamide Cariprazine Vraylar Explained Effects on the cariprazine exposure has not been evaluated and the net effect is unclear Details Rufinamide Amlodipine Amvaz® Reduced amLODIPine exposure Details Rufinamide Calcifediol Rayaldee Altered serum levels of calcifediol Details Rufinamide Estradiol Delestrogen Reduced contraceptive exposure, reduced efficacy of combination contraceptives and an increased risk of breakthrough bleeding/cont... Details Rufinamide Estradiol Topical Divigel Reduced contraceptive exposure, reduced efficacy of combination contraceptives and an increased risk of breakthrough bleeding/cont... Details Rufinamide Estradiol Transdermal Patch Alora® Reduced contraceptive exposure, reduced efficacy of combination contraceptives and an increased risk of breakthrough bleeding/cont... Details Rufinamide Fentanyl Transdermal Patch Duragesic® Reduced exposure of fentaNYL, reduced efficacy of fentaNYL and/or onset of opioid withdrawal symptoms Details Rufinamide Hydroxychloroquine Plaquenil Impaired antiepileptic activity Details Rufinamide Levonorgestrel After banger Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Rufinamide Levonorgestrel Intrauterine System Kyleena Reduced levonorgestrel exposure and increased risk of breakthrough bleeding and/or contraceptive failure Details Rufinamide Lumateperone Caplyta Reduced lumateperone exposure Details Rufinamide Medroxyprogesterone Amen® Reduced contraceptive exposure, reduced efficacy of combination contraceptives and an increased risk of breakthrough bleeding/cont... Details Rufinamide Medroxyprogesterone Injection Depo-Provera Reduced contraceptive exposure, reduced efficacy of combination contraceptives and an increased risk of breakthrough bleeding/cont... Details Rufinamide Nifedipine Adalat® Reduced NIFEdipine exposure Details Rufinamide Orlistat Alli Reduced efficacy of anticonvulsant DetailsModerate
Rufinamide Folic Acid Folacin Reduced folic acid exposure and reduced efficacy of folic acid Details Rufinamide Hydrocortisone Ala-Cort Reduced hydrocortisone exposure Details Rufinamide Hydrocortisone Injection A-Hydrocort® Reduced hydrocortisone exposure Details Rufinamide Nimodipine Nimotop Reduced nimodipine plasma concentrations and lack of nimodipine efficacy DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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