Exemestane

32 interactions 101 cited references
Also sold as: Aromasin Aromasin®
About Exemestane

Exemestane is used to treat early breast cancer in women who have experienced menopause ('change of life'; end of monthly menstrual periods) and who have already been treated with a medication called tamoxifen (Nolvadex) for 2 to 3 years. This medication is also used to treat breast cancer in women who have experienced… Read the full Exemestane drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 9, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Exemestane Darolutamide Nubeqa Increased exposure of OATP1B1 or OATP1B3 substrates Details Exemestane Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Exemestane Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Exemestane Apalutamide Erleada Reduced OATP1B1 substrates exposure and reduced efficacy of OATP1B1 substrates Details Exemestane Carbamazepine Carbatrol Reduced exemestane exposure Details Exemestane Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Exemestane Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Exemestane Elexacaftor Increased OATP1B1 substrate exposure Details Exemestane Eltrombopag Alvaiz Increased OATP1B1 substrates exposure and an increased risk of OATP1B1 substrates-related adverse reactions Details Exemestane Enzalutamide Xtandi Reduced exemestane exposure Details Exemestane Fosphenytoin Cerebyx Reduced exemestane exposure Details Exemestane Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Exemestane Leniolisib Joenja Increased OATP1B1 substrate exposure Details Exemestane Mitotane Lysodren Reduced exemestane exposure Details Exemestane Phenytoin Dilantin Reduced exemestane exposure Details Exemestane Primidone Mysoline Reduced exemestane exposure Details Exemestane Rifabutin Mycobutin Reduced exemestane exposure Details Exemestane Rifampin Rifadin Reduced exemestane exposure Details Exemestane Rifapentine Priftin Reduced exemestane exposure Details Exemestane Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details Exemestane St John's Wort Reduced exemestane exposure Details Exemestane Voclosporin Lupkynis Increased OATP1B1 substrate exposure Details

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