Acenocoumarol

95 interactions 5 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Injection Bicalutamide Dipyridamole Allopurinol Ibrutinib Fluorouracil Injection

1 Contraindicated 68 Major 25 Moderate 1 Minor

All (95) Contraindicated (1) Major (68) Moderate (25) Minor (1)

Contraindicated

Acenocoumarol Defibrotide Injection Defitelio Increased risk of bleeding Details

Major

Acenocoumarol Sertraline Explained An increased risk of bleeding Details Acenocoumarol Simvastatin Flolipid Explained An increased risk of bleeding and increased risk of rhabdomyolysis Details Acenocoumarol Allopurinol Aloprim Increased INR Details Acenocoumarol Allopurinol Injection Aloprim Increased INR Details Acenocoumarol Amoxicillin Amoxi Drop Increased INR and increased risk of bleeding Details Acenocoumarol Apixaban Eliquis Explained An increased risk of bleeding and can cause serious, potentially fatal bleeding Details Acenocoumarol Aspirin Acuprin® Increased risk of bleeding Details Acenocoumarol Aspirin Rectal Aspirin Increased risk of bleeding Details Acenocoumarol Betrixaban Bevyxxa® Increased risk of bleeding Details Acenocoumarol Bicalutamide Casodex An increased risk of bleeding Details Acenocoumarol Anagrelide Agrylin Increased risk of bleeding Details Acenocoumarol Bromfenac Ophthalmic Bromday® An increased risk of bleeding Details Acenocoumarol Capecitabine Xeloda Increased vitamin K antagonist exposure and an increased risk of bleeding Details Acenocoumarol Caplacizumab-Yhdp Injection Cablivi An increased risk of bleeding Details Acenocoumarol Clopidogrel Plavix Increased risk of bleeding Details Acenocoumarol Dabigatran Pradaxa® An increased risk of bleeding Details Acenocoumarol Dabigatran Etexilate An increased risk of bleeding Details Acenocoumarol Dalteparin Injection Fragmin Increased risk of bleeding Details Acenocoumarol Diclofenac Ophthalmic Voltaren® Eye Drops An increased risk of bleeding Details Acenocoumarol Diclofenac Topical (Actinic Keratosis) Pennsaid An increased risk of bleeding Details Acenocoumarol Diclofenac Topical (Arthritis Pain) Pennsaid® An increased risk of bleeding Details Acenocoumarol Diclofenac Transdermal Patch Flector An increased risk of bleeding Details Acenocoumarol Dipyridamole Permole® Increased risk of bleeding Details Acenocoumarol Doxycycline Injection Acticlate An increased risk of bleeding Details Acenocoumarol Edoxaban Savaysa Increased risk of bleeding Details Acenocoumarol Enoxaparin Lovenox Increased risk of bleeding Details Acenocoumarol Enoxaparin Injection Lovenox Increased risk of bleeding Details Acenocoumarol Epoprostenol Flolan Increased risk of bleeding Details Acenocoumarol Erlotinib Tarceva An increased risk of bleeding Details Acenocoumarol Etodolac Lodine An increased risk of bleeding Details Acenocoumarol Fenoprofen Fenopron An increased risk of bleeding Details Acenocoumarol Fluorouracil Adrucil Increased vitamin K antagonist exposure and an increased risk of bleeding Details Acenocoumarol Fluorouracil Injection Adrucil Increased vitamin K antagonist exposure and an increased risk of bleeding Details Acenocoumarol Fluorouracil Topical Carac Increased vitamin K antagonist exposure and an increased risk of bleeding Details Acenocoumarol Flurbiprofen Ansaid An increased risk of bleeding Details Acenocoumarol Flurbiprofen Ophthalmic Ocufen An increased risk of bleeding Details Acenocoumarol Ibrutinib Imbruvica Increased risk of bleeding Details Acenocoumarol Ibuprofen Addaprin An increased risk of bleeding Details Acenocoumarol Iloprost Aurlumyn Increased risk of bleeding Details

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