Acenocoumarol

95 interactions 5 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Defibrotide Injection Bicalutamide Dipyridamole Allopurinol Ibrutinib Fluorouracil Injection

1 Contraindicated 68 Major 25 Moderate 1 Minor

All (95) Contraindicated (1) Major (68) Moderate (25) Minor (1)

Moderate

Acenocoumarol Acetaminophen And Codeine Capital® & Codeine Explained Potentiation of anticoagulant effect Details Acenocoumarol Amitriptyline Elavil Explained An increased risk of bleeding Details Acenocoumarol Acetaminophen Acephen Potentiation of anticoagulant effect Details Acenocoumarol Acetaminophen Injection Acephen Potentiation of anticoagulant effect Details Acenocoumarol Acetaminophen Rectal Acephen Potentiation of anticoagulant effect Details Acenocoumarol Azathioprine Azasan Reduced acenocoumarol therapeutic efficacy Details Acenocoumarol Capsaicin Arthricare for Women Moisturizing Increased risk of bleeding Details Acenocoumarol Capsaicin Topical Aspercreme Warming® Increased risk of bleeding Details Acenocoumarol Capsaicin Transdermal Patch Aspercreme Warming® Patch Increased risk of bleeding Details Acenocoumarol Dexamethasone Injection Decadron Increased risk of bleeding or diminished effects of acenocoumarol Details Acenocoumarol Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Increased risk of bleeding or diminished effects of acenocoumarol Details Acenocoumarol Fludrocortisone Acetate Florinef® Increased risk of bleeding or diminished effects of acenocoumarol Details Acenocoumarol Glimepiride Amaryl Excessive hypoglycemia Details Acenocoumarol Hydrocortisone Ala-Cort Increased risk of bleeding or diminished effects of acenocoumarol Details Acenocoumarol Hydrocortisone Injection A-Hydrocort® Increased risk of bleeding or diminished effects of acenocoumarol Details Acenocoumarol Ibritumomab Injection Zevalin® An increased risk of bleeding and hemorrhage Details Acenocoumarol Icosapent Ethyl Vascepa An increased risk of bleeding Details Acenocoumarol Lactulose Cholac® Elevated International Normalized Ratio serum values with potentiation of anticoagulation effects Details Acenocoumarol Lansoprazole Prevacid Elevations in International Normalized Ratio serum values and potentiation of anticoagulation effects Details Acenocoumarol Mercaptopurine Purinethol® Reduced acenocoumarol therapeutic efficacy Details Acenocoumarol Methimazole Felanorm Decreased anticoagulant effectiveness Details Acenocoumarol Miconazole Buccal Oravig An increased risk of bleeding Details Acenocoumarol Miconazole Topical Aloe Vesta Antifungal An increased risk of bleeding Details Acenocoumarol Miconazole Vaginal Lagicam An increased risk of bleeding Details Acenocoumarol Miconazole Aloe Vesta Antifungal An increased risk of bleeding Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.