Panobinostat

63 interactions 4 explained in plain English

Also sold as: Farydak Farydak®

About Panobinostat

Panobinostat is used in combination with bortezomib (Velcade) and dexamethasone to treat people with multiple myeloma (a type of cancer of the bone marrow) who have already been treated two other medications, including bortezomib (Velcade). Panobinostat is in a class of medications called histone deacetylase (HDAC) inh… Read the full Panobinostat drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Ketoconazole Topical Oxaliplatin Injection Inotuzumab Ozogamicin Injection Buprenorphine Encorafenib Octreotide

1 Contraindicated 62 Major

All (63) Contraindicated (1) Major (62)

Contraindicated

Panobinostat Ketoconazole Topical Extina® Foam Increased panobinostat exposure and an increased risk of QT interval prolongation Details

Major

Panobinostat Amitriptyline Elavil Explained Increased risk of QT interval prolongation Details Panobinostat Sertraline Explained An increased risk of QT interval prolongation Details Panobinostat Buprenorphine Belbuca Explained An increased risk of QT interval prolongation Details Panobinostat Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Panobinostat Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Panobinostat Arsenic Trioxide Trisenox Increased risk of QT interval prolongation Details Panobinostat Aripiprazole Injection Abilify Increased risk of QT interval prolongation Details Panobinostat Arsenic Trioxide Injection Trisenox Increased risk of QT interval prolongation Details Panobinostat Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Panobinostat Azithromycin AzaSite Increased risk of QT interval prolongation Details Panobinostat Alfuzosin UroXatral Increased risk of QT interval prolongation Details Panobinostat Anagrelide Agrylin Increased risk of QT interval prolongation Details Panobinostat Bedaquiline Sirturo Increased risk of QT interval prolongation Details Panobinostat Chloroquine Aralen® Increased risk of QT interval prolongation Details Panobinostat Dasatinib Phyrago Increased risk of QT interval prolongation Details Panobinostat Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Panobinostat Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Panobinostat Disopyramide Norpace Increased risk of QT interval prolongation Details Panobinostat Dofetilide Tikosyn Increased risk of QT interval prolongation Details Panobinostat Dolasetron Anzemet Increased risk of QT interval prolongation Details Panobinostat Dolasetron Injection Anzemet Increased risk of QT interval prolongation Details Panobinostat Encorafenib Braftovi Increased risk of QT interval prolongation Details Panobinostat Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Panobinostat Eribulin Injection Halaven Increased risk of QT interval prolongation Details Panobinostat Famotidine Calmicid Increased risk of QT interval prolongation Details Panobinostat Famotidine Injection Calmicid Increased risk of QT interval prolongation Details Panobinostat Felbamate Felbatol Increased risk of QT interval prolongation Details Panobinostat Flecainide Tambocor® Increased risk of QT interval prolongation Details Panobinostat Foscarnet Injection Foscavir Increased risk of QT interval prolongation Details Panobinostat Fostemsavir Rukobia Increased risk of torsade de pointes Details Panobinostat Galantamine Razadyne Increased risk of QT interval prolongation Details Panobinostat Gatifloxacin Ophthalmic Zymar® Increased risk of QT interval prolongation Details Panobinostat Gemifloxacin Factive Increased risk of QT interval prolongation Details Panobinostat Glasdegib Daurismo Increased risk of QT interval prolongation Details Panobinostat Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Panobinostat Granisetron Transdermal Patch Sancuso Increased risk of QT interval prolongation Details Panobinostat Granisetron Injection Granisol Increased risk of QT interval prolongation Details Panobinostat Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Panobinostat Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.