Cefadroxil

30 interactions 109 cited references
Also sold as: Duricef® Ultracef®
About Cefadroxil

Cefadroxil is used to treat certain infections caused by bacteria such as infections of the skin, throat, tonsils, and urinary tract. Cefadroxil is in a class of medications called cephalosporin antibiotics. It works by killing bacteria. Antibiotics such as cefadroxil will not work for colds, flu, or other viral infect… Read the full Cefadroxil drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Azathioprine Cholera Vaccine, Live Desogestrel Methotrexate Injection Levonorgestrel Intrauterine System Exenatide Injection
27 Major 3 Moderate
All (30) Major (27) Moderate (3)

Major

Cefadroxil Azathioprine Azasan An increased risk of hepatotoxicity Details Cefadroxil Cholera Vaccine, Live Reduced immune response to the cholera vaccine Details Cefadroxil Desogestrel Decreased contraceptive effectiveness Details Cefadroxil Dienogest Decreased contraceptive effectiveness Details Cefadroxil Drospirenone Decreased contraceptive effectiveness Details Cefadroxil Estradiol Delestrogen Decreased contraceptive effectiveness Details Cefadroxil Ethinyl Estradiol Decreased contraceptive effectiveness Details Cefadroxil Ethynodiol Decreased contraceptive effectiveness Details Cefadroxil Exenatide Bydureon Reduced oral antibiotics absorption and reduced efficacy of oral antibiotics Details Cefadroxil Furosemide Disal Increased risk of cephalosporin-induced nephrotoxicity Details Cefadroxil Gestodene Decreased contraceptive effectiveness Details Cefadroxil Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Cefadroxil Levonorgestrel After banger Decreased contraceptive effectiveness Details Cefadroxil Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Cefadroxil Mestranol Decreased contraceptive effectiveness Details Cefadroxil Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Cefadroxil Nomegestrol Decreased contraceptive effectiveness Details Cefadroxil Norethindrone Aygestin Decreased contraceptive effectiveness Details Cefadroxil Norgestimate Decreased contraceptive effectiveness Details Cefadroxil Norgestrel Decreased contraceptive effectiveness Details Cefadroxil Warfarin Coumadin An increased risk of bleeding Details Cefadroxil Estradiol Topical Divigel Decreased contraceptive effectiveness Details Cefadroxil Estradiol Transdermal Patch Alora® Decreased contraceptive effectiveness Details Cefadroxil Exenatide Injection Bydureon Reduced oral antibiotics absorption and reduced efficacy of oral antibiotics Details Cefadroxil Furosemide Injection Disal Increased risk of cephalosporin-induced nephrotoxicity Details Cefadroxil Levonorgestrel Intrauterine System Kyleena Decreased contraceptive effectiveness Details Cefadroxil Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details

Moderate

Cefadroxil Lixisenatide Delayed therapeutic effect Details Cefadroxil Typhoid Vaccine, Live Vivotif A decreased immunological response to the typhoid vaccine Details Cefadroxil Lixisenatide Injection Adlyxin® Delayed therapeutic effect Details

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