Danazol

28 interactions 252 cited references
Also sold as: Danocrine®
About Danazol

Danazol is used to treat endometriosis (a condition in which the type of tissue that lines the uterus [womb] grows in other areas of the body and causes infertility, pain before and during menstrual periods, pain during and after sexual activity, and heavy or irregular bleeding)..Danazol is also used to treat fibrocyst… Read the full Danazol drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Major

Danazol Azathioprine Azasan An increased risk of hepatotoxicity Details Danazol Atorvastatin Atorvaliq An increased risk of myopathy or rhabdomyolysis Details Danazol Anisindione Increased risk of bleeding Details Danazol Bupropion Aplenzin Lowering of the seizure threshold Details Danazol Carbamazepine Carbatrol Increased carBAMazepine exposure and an increased risk of carBAMazepine toxicity Details Danazol Dicumarol Increased risk of bleeding Details Danazol Fluvastatin Lescol An increased risk of myopathy or rhabdomyolysis Details Danazol Insulin Aspart, Recombinant Fiasp Reduced blood glucose lowering effect of insulin Details Danazol Insulin Glargine, Recombinant Basaglar Reduced blood glucose lowering effect of insulin Details Danazol Insulin Icodec-Abae Awiqli Reduced efficacy of insulin icodec-abae Details Danazol Levoketoconazole Recorlev Increased risk of serious hepatotoxicity and drug-induced liver injury Details Danazol Lovastatin Altocor® An increased risk of myopathy or rhabdomyolysis Details Danazol Mercaptopurine Purinethol® An increased risk of hepatotoxicity Details Danazol Methotrexate Jylamvo Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details Danazol Pexidartinib Turalio Hepatotoxicity Details Danazol Phenprocoumon Increased risk of bleeding Details Danazol Tacrolimus Astagraf Increased tacrolimus exposure and an increased risk of toxicity Details Danazol Warfarin Coumadin An increased risk of bleeding Details Danazol Methotrexate Injection Abitrexate® Increased methotrexate exposure, an increased risk of methotrexate-related severe adverse reactions, reduced active metabolite for... Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.