Paclitaxel

Major

Paclitaxel Abametapir Explained Increased exposure of CYP3A4 substrate Details Paclitaxel Asciminib Scemblix Increased CYP3A4 exposure and an increased risk of CYP3A4-related adverse reactions Details Paclitaxel Belumosudil Rezurock Explained Increased OATP1B1 substrate exposure Details Paclitaxel Abiraterone Abirtega Increased PACLitaxel exposure Details Paclitaxel Capmatinib Tabrecta Increased PACLitaxel exposure Details Paclitaxel Cisplatin Injection Platinol-AQ® Increased PACLitaxel exposure Details Paclitaxel Clopidogrel Plavix Increased PACLitaxel exposure Details Paclitaxel Clotrimazole Aardora Anti-Fungal Maximum Strength Increased PACLitaxel exposure Details Paclitaxel Clotrimazole Lozenge Mycelex® Increased PACLitaxel exposure Details Paclitaxel Clotrimazole Topical Cruex Antifungal Increased PACLitaxel exposure Details Paclitaxel Clotrimazole Vaginal Gyne-Lotrimin 3® Cream Increased PACLitaxel exposure Details Paclitaxel Cyclosporine Injection Atopica Increased PACLitaxel exposure Details Paclitaxel Cyclosporine Ophthalmic Cequa Increased PACLitaxel exposure Details Paclitaxel Darolutamide Nubeqa Increased exposure of OATP1B1 or OATP1B3 substrates Details Paclitaxel Deferasirox Exjade Increased PACLitaxel exposure Details Paclitaxel Dexamethasone Injection Decadron Reduced PACLitaxel exposure Details Paclitaxel Dexamethasone Ophthalmic Dexacidin® (as a combination product containing Dexamethasone, Neomycin, Polymyxin B) Reduced PACLitaxel exposure Details Paclitaxel Doxorubicin Adriamycin Increase in exposure of DOXOrubicin and its metabolites Details Paclitaxel Enasidenib Idhifa Altered (increased/reduced) PACLitaxel exposure and an increased risk of PACLitaxel-related adverse effects or reduced efficacy of... Details Paclitaxel Gemfibrozil Lopid Increased PACLitaxel exposure Details Paclitaxel Idarubicin Idamycin Increased risk of cardiotoxicity Details Paclitaxel Irbesartan Avapro Increased PACLitaxel exposure Details Paclitaxel Istradefylline Nourianz Increased PACLitaxel exposure Details Paclitaxel Ketoconazole Topical Extina® Foam Increased PACLitaxel exposure and an increased risk of PACLitaxel-related adverse reactions Details Paclitaxel Lanreotide Injection Somatuline Altered exposure to CYP3A4 substrate Details Paclitaxel Lefamulin Xenleta Increased sensitive CYP3A4 substrate exposure and an increased risk of sensitive CYP3A4 substrate-related toxicities associated wi... Details Paclitaxel Leflunomide Arava Increased exposure of CYP2C8 substrate Details Paclitaxel Leniolisib Joenja Increased OATP1B1/OATP1B3 substrate exposure Details Paclitaxel Letermovir Injection Prevymis Increased PACLitaxel exposure and an increased risk of PACLitaxel-related adverse reactions Details Paclitaxel Mitapivat Aqvesme Reduced PACLitaxel exposure Details Paclitaxel Nafcillin Injection Unipen® Injection Reduced PACLitaxel exposure Details Paclitaxel Nevirapine Viramune Reduced PACLitaxel exposure Details Paclitaxel Octreotide Bynfezia Increased exposure of CYP3A4 substrates with narrow therapeutic index Details Paclitaxel Octreotide Injection Bynfezia Increased exposure of CYP3A4 substrates with narrow therapeutic index Details

Moderate

Paclitaxel Simvastatin Flolipid Explained Altered (increased/reduced) PACLitaxel exposure, reduced PACLitaxel exposure and an increased PACLitaxel-related adverse reactions... Details Paclitaxel Encorafenib Braftovi Increased OATP1B1 substrate exposure, increased OATP1B3 substrate exposure, increased risk of OATP1B1 substrate-related toxicities... Details Paclitaxel Felodipine Plendil® Altered (increased/reduced) PACLitaxel exposure, reduced PACLitaxel exposure and an increased PACLitaxel-related adverse reactions... Details Paclitaxel Finerenone Kerendia Increased CYP2C8 substrate exposure and an increased risk of CYP2C8 substrate-related adverse effects Details Paclitaxel Lovastatin Altocor® Altered (increased/reduced) PACLitaxel exposure, reduced PACLitaxel exposure and an increased PACLitaxel-related adverse reactions... Details Paclitaxel Midazolam Nasal Spray Nayzilam Altered (increased/reduced) PACLitaxel exposure, reduced PACLitaxel exposure and an increased PACLitaxel-related adverse reactions... Details