Skullcap

20 interactions
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

16 Moderate 4 Minor
All (20) Moderate (16) Minor (4)

Moderate

Skullcap Aspirin Acuprin® Increased risk of bleeding Details Skullcap Aspirin Rectal Aspirin Increased risk of bleeding Details Skullcap Anagrelide Agrylin Increased risk of bleeding Details Skullcap Becaplermin Topical Regranex Increased risk of bleeding Details Skullcap Clopidogrel Plavix Increased risk of bleeding Details Skullcap Dalteparin Injection Fragmin Increased risk of bleeding Details Skullcap Defibrotide Injection Defitelio Increased risk of bleeding Details Skullcap Dipyridamole Permole® Increased risk of bleeding Details Skullcap Enoxaparin Lovenox Increased risk of bleeding Details Skullcap Enoxaparin Injection Lovenox Increased risk of bleeding Details Skullcap Epoprostenol Flolan Increased risk of bleeding Details Skullcap Fondaparinux Arixtra Increased risk of bleeding Details Skullcap Fondaparinux Injection Arixtra Increased risk of bleeding Details Skullcap Heparin Increased risk of bleeding Details Skullcap Heparin Injection Lipo-Hepin® Increased risk of bleeding Details Skullcap Iloprost Aurlumyn Increased risk of bleeding Details

Minor

Skullcap Diazepam Nasal Spray Valtoco Increased central nervous system depression Details Skullcap Diazepam Rectal Diastat Increased central nervous system depression Details Skullcap Midazolam Nasal Spray Nayzilam Increased central nervous system depression Details Skullcap Midazolam Injection Nayzilam Increased central nervous system depression Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.