Digitoxin

14 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Furosemide Injection
1 Major 13 Moderate
All (14) Major (1) Moderate (13)

Major

Digitoxin Furosemide Injection Disal Digitoxin toxicity (nausea, vomiting, cardiac arrhythmias) Details

Moderate

Digitoxin Atenolol Tenormin Explained Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Acebutolol Sectral® Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Amphotericin B Injection Abelcet Hypokalemia and digitalis toxicity (nausea, vomiting, visual disturbances, cardiac arrhythmias) Details Digitoxin Betaxolol Betoptic S Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Betaxolol Ophthalmic Betoptic® Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Bisoprolol Zebeta® Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Cholestyramine Resin Locholest® Decreased digitoxin effectiveness Details Digitoxin Esmolol Brevibloc Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Labetalol Normodyne® Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Levobunolol Ophthalmic AKBeta® Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Nadolol Corgard Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Nebivolol Bystolic Increased risk of bradycardia and possible digitalis glycoside toxicity Details Digitoxin Penbutolol Levatol® Increased risk of bradycardia and possible digitalis glycoside toxicity Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.