Pentostatin Injection

22 interactions 128 cited references
Also sold as: Nipent Nipent®
About Pentostatin Injection

Pentostatin is used to treat hairy cell leukemia (cancer of a certain type of white blood cell). Pentostatin is a type of antibiotic that is only used in cancer chemotherapy. It works by slowing or stopping the growth of cancer cells in your body. Read the full Pentostatin Injection drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Yellow Fever Vaccine Smallpox Monkeypox Vaccine Bacillus Of Calmette And Guerin Vaccine, Live Rubella Virus Vaccine, Live Mumps Virus Vaccine, Live Dengue Tetravalent Vaccine, Live
9 Contraindicated 12 Major 1 Moderate
All (22) Contraindicated (9) Major (12) Moderate (1)

Contraindicated

Pentostatin Injection Bacillus Of Calmette And Guerin Vaccine, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Dengue Tetravalent Vaccine, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Measles Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Mumps Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Rubella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Smallpox Monkeypox Vaccine An increased risk of infection by the live vaccine Details Pentostatin Injection Typhoid Vaccine Typhim VI® An increased risk of infection by the live vaccine Details Pentostatin Injection Varicella Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Yellow Fever Vaccine Stamaril An increased risk of infection by the live vaccine Details

Major

Pentostatin Injection Adenovirus Vaccine Type 4, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Adenovirus Vaccine Type 7, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Cholera Vaccine Ipol An increased risk of infection by the live vaccine Details Pentostatin Injection Cyclophosphamide Cytoxan® Cardiac toxicity Details Pentostatin Injection Ebola Zaire Vaccine, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Fludarabine An increased risk of severe and fatal pulmonary toxicity Details Pentostatin Injection Influenza Virus Vaccine, Live An increased risk of infection by the live vaccine Details Pentostatin Injection Islatravir Reduced islatravir-triphosphate exposure Details Pentostatin Injection Nelarabine Reduced conversion of nelarabine to its active moiety, resulting in decreased nelarabine efficacy Details Pentostatin Injection Pegademase Bovine Reduced efficacy of both drugs Details Pentostatin Injection Pexidartinib Turalio Hepatotoxicity Details Pentostatin Injection Rotavirus Vaccine, Live An increased risk of infection by the live vaccine Details

Moderate

Pentostatin Injection Vidarabine Vidarabine toxicity (GI upset, CNS disturbance) Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.