Celecoxib Interactions
Celecoxib is used to relieve pain, tenderness, swelling and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), and ankylosing spondylitis (arthritis that mainly affects the spine). Celecoxib is also used to treat juvenile rheumatoid arthritis (a type of arthritis that affects children) in children 2 years of age and older. Celecoxib is also used to treat painful menstrual periods and to relieve other types of short-term pain including pain caused by injuries, surgery and other medical or dental procedures, or medical conditions that last for a limited time. Celecoxib is in a class of NSAIDs called COX-2 inhibitors. It works by stopping the body's production of a substance that causes pain and inflammation.
Brand Names Associated with Celecoxib
- Celebrex®
- Celecoxib
- Consensi® (as a combination product containing Amlodipine, Celecoxib)
- Elyxyb®
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- Contraindicated
- Major
- Prednisone
- Apixaban
- Warfarin
- Hydrochlorothiazide
- Sertraline
- Ticagrelor
- Escitalopram
- Furosemide
- Trazodone
- Fluoxetine
- Duloxetine
- Meloxicam
- Clopidogrel
- Citalopram
- Aspirin
- Ibuprofen
- Venlafaxine
- Spironolactone
- Amitriptyline
- Paroxetine
- Rivaroxaban
- Naproxen
- Abciximab
- Aceclofenac
- Acemetacin
- Acenocoumarol
- Adagrasib
- Amiloride
- Amineptine
- Amitriptylinoxide
- Amoxapine
- Amtolmetin Guacil
- Anagrelide
- Ardeparin
- Argatroban
- Asciminib
- Balsalazide
- Bemetizide
- Bemiparin
- Bendroflumethiazide
- Benzthiazide
- Betamethasone
- Betrixaban
- Bismuth Subsalicylate
- Bivalirudin
- Bromfenac
- Budesonide
- Bufexamac
- Bumetanide
- Cangrelor
- Capecitabine
- Ceritinib
- Certoparin
- Chlorothiazide
- Chlorthalidone
- Choline Magnesium Trisalicylate
- Choline Salicylate
- Cilostazol
- Clomipramine
- Clonixin
- Clopamide
- Cortisone
- Cyclopenthiazide
- Cyclosporine
- Cyclothiazide
- Dabigatran Etexilate
- Dabrafenib
- Dalteparin
- Danaparoid
- Deflazacort
- Desipramine
- Desirudin
- Desmopressin
- Desvenlafaxine
- Dexamethasone
- Dexibuprofen
- Dexketoprofen
- Diazoxide
- Dibenzepin
- Diflunisal
- Digoxin
- Dipyridamole
- Dipyrone
- Dothiepin
- Doxepin
- Droxicam
- Edoxaban
- Emtricitabine
- Enoxaparin
- Eplerenone
- Epoprostenol
- Eptifibatide
- Ethacrynic Acid
- Etodolac
- Etofenamate
- Etoricoxib
- Etozolin
- Felbinac
- Fenoprofen
- Fepradinol
- Feprazone
- Feverfew
- Floctafenine
- Fluconazole
- Flufenamic Acid
- Fluocortolone
- Flurbiprofen
- Fluvoxamine
- Fondaparinux
- Ginkgo
- Gossypol
- Heparin
- Hydrocortisone
- Hydroflumethiazide
- Iloprost
- Imipramine
- Indapamide
- Inotersen
- Ivosidenib
- Ketoprofen
- Lepirudin
- Levomilnacipran
- Lithium
- Lofepramine
- Lornoxicam
- Loxoprofen
- Lumiracoxib
- Magnesium Salicylate
- Mavacamten
- Meadowsweet
- Meclofenamate
- Mefenamic Acid
- Melitracen
- Melphalan
- Mesalamine
- Methotrexate
- Methyclothiazide
- Methylprednisolone
- Metolazone
- Milnacipran
- Morniflumate
- Nabumetone
- Nadroparin
- Nefazodone
- Nepafenac
- Niflumic Acid
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Nitisinone
- Nortriptyline
- Olsalazine
- Opipramol
- Oxaprozin
- Oxyphenbutazone
- Paramethasone
- Parecoxib
- Parnaparin
- Pemetrexed
- Pentosan Polysulfate Sodium
- Pentoxifylline
- Phenindione
- Phenobarbital
- Phenprocoumon
- Phenylbutazone
- Phenyl Salicylate
- Piketoprofen
- Piretanide
- Piroxicam
- Polythiazide
- Potassium Citrate
- Prasugrel
- Prednisolone
- Primidone
- Proglumetacin
- Propyphenazone
- Proquazone
- Protein C
- Protriptyline
- Quinethazone
- Reviparin
- Rofecoxib
- Salicylamide
- Salicylic Acid
- Salsalate
- Selexipag
- Sibutramine
- Sodium Salicylate
- Sparsentan
- Sulfasalazine
- Sulfinpyrazone
- Sulindac
- Sulodexide
- Tacrolimus
- Tenofovir Alafenamide
- Tenofovir Disoproxil Fumarate
- Tenoxicam
- Tianeptine
- Tiaprofenic Acid
- Ticlopidine
- Tinzaparin
- Tirofiban
- Tocilizumab
- Tolfenamic Acid
- Tolmetin
- Torsemide
- Treprostinil
- Triamterene
- Trichlormethiazide
- Trimipramine
- Trolamine Salicylate
- Valdecoxib
- Vilazodone
- Vorapaxar
- Vortioxetine
- Xipamide
- Moderate
- Metoprolol
- Losartan
- Sacubitril; Valsartan
- Carvedilol
- Lisinopril
- Atenolol
- Propranolol
- Acebutolol
- Amiodarone
- Apalutamide
- Azilsartan
- Azilsartan Medoxomil
- Benazepril
- Betaxolol
- Bisoprolol
- Candesartan
- Captopril
- Carteolol
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What Do The Severity Ratings Mean?
Contraindicated
These drugs, generally, should not be used together simultaneously due to the high risk of severe adverse effects. Combining these medications can lead to dangerous health outcomes and should be strictly avoided unless otherwise instructed by your provider.
Major
This interaction could result in very serious and potentially life-threatening consequences. If you are taking this drug combination, it is very important to be under close medical supervision to minimize severe side effects and ensure your safety. It may be necessary to change a medication or dosage to prevent harm.
Moderate
This interaction has the potential to worsen your medical condition or alter the effectiveness of your treatment. It's important that you are monitored closely and you potentially may need to make adjustments in your treatment plan or drug dosage to maintain optimal health.
Minor
While this interaction is unlikely to cause significant problems, it could intensify side effects or reduce the effectiveness of one or both medications. Monitoring for changes in symptoms and your condition is recommended, and adjustments may be made if needed to manage any increased or more pronounced side effects.
Disclaimer: The information provided on this page is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional regarding your specific circumstances and medical conditions.
Drug interaction information is compilated from several drug compendia, including:
- Gold Standard Drug Database
- Micromedix
- Lexicomp
- PubMed
The information posted is fact-checked by HelloPharmacist clinicians and reviewed quarterly.