Valsartan

41 interactions 1 explained in plain English
Also sold as: Diovan Diovan® Prexxartan
About Valsartan

Valsartan is an angiotensin II receptor antagonist used to treat high blood pressure, heart failure, and improve survival after a heart attack. Read the full Valsartan drug information page →

Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jun 30, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Moderate

Valsartan Asenapine Transdermal Patch Secuado An increased risk of hypotension Details Valsartan Bromfenac Ophthalmic Bromday® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Diclofenac Ophthalmic Voltaren® Eye Drops Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Diclofenac Topical (Actinic Keratosis) Pennsaid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Diclofenac Topical (Arthritis Pain) Pennsaid® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Diclofenac Transdermal Patch Flector Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Encorafenib Braftovi Increased OATP1B1 substrate exposure, increased OATP1B3 substrate exposure, increased risk of OATP1B1 substrate-related toxicities... Details Valsartan Etodolac Lodine Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Fenoprofen Fenopron Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Flurbiprofen Ansaid Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Flurbiprofen Ophthalmic Ocufen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Ibuprofen Addaprin Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Insulin Degludec (Rdna Origin) Injection Ryzodeg® (as a combination product containing Insulin Degludec and Insulin Aspart) Increased risk of hypoglycemia Details Valsartan Insulin Detemir (Rdna Origin) Injection Levemir Increased risk of hypoglycemia Details Valsartan Insulin Glulisine (Rdna Origin) Injection Apidra Increased risk of hypoglycemia Details Valsartan Ketoprofen Actron® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Ketorolac Acular Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Ketorolac Injection Acular Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Ketorolac Nasal Spray Sprix Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Ketorolac Ophthalmic Acular Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Meclofenamate Meclodium® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Mefenamic Acid Ponstel® Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Meloxicam Alloxate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Meloxicam Injection Alloxate Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details Valsartan Nabumetone Relafen Reduced antihypertensive effect and renal dysfunction and/or increased blood pressure Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.