Seladelpar

25 interactions 1 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Asciminib Capecitabine Leniolisib Colesevelam Colestipol Fluorouracil Topical
9 Major 16 Moderate
All (25) Major (9) Moderate (16)

Major

Seladelpar Asciminib Scemblix Increased BCRP substrate exposure and an increased risk of BCRP substrate-related adverse effects Details Seladelpar Capecitabine Xeloda Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Seladelpar Cholestyramine Resin Locholest® Reduced seladelpar exposure and reduced efficacy of seladelpar Details Seladelpar Colesevelam Welchol Reduced seladelpar exposure and reduced efficacy of seladelpar Details Seladelpar Colestipol Colestid Reduced seladelpar exposure and reduced efficacy of seladelpar Details Seladelpar Fluorouracil Adrucil Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Seladelpar Fluorouracil Injection Adrucil Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Seladelpar Fluorouracil Topical Carac Increased exposure of CYP2C9 substrates and an increased risk of CYP2C9 substrates-related adverse effects Details Seladelpar Leniolisib Joenja Increased BCRP substrate exposure Details

Moderate

Seladelpar Belumosudil Rezurock Explained Increased seladelpar exposure Details Seladelpar Bempedoic Acid Nexletol Increased seladelpar exposure Details Seladelpar Cyclosporine Injection Atopica Increased seladelpar exposure Details Seladelpar Cyclosporine Ophthalmic Cequa Increased seladelpar exposure Details Seladelpar Darolutamide Nubeqa Increased seladelpar exposure Details Seladelpar Eluxadoline Viberzi Increased seladelpar exposure Details Seladelpar Enasidenib Idhifa Increased seladelpar exposure Details Seladelpar Encorafenib Braftovi Increased seladelpar exposure Details Seladelpar Fostemsavir Rukobia Increased seladelpar exposure Details Seladelpar Gemfibrozil Lopid Increased seladelpar exposure Details Seladelpar Ibrexafungerp Brexafemme Increased seladelpar exposure Details Seladelpar Ketoconazole Topical Extina® Foam Increased seladelpar exposure Details Seladelpar Lefamulin Xenleta Increased seladelpar exposure Details Seladelpar Lenacapavir Injection Sunlenca Increased seladelpar exposure and an increased risk of seladelpar-related adverse reactions Details Seladelpar Lenacapavir Oral Sunlenca Increased seladelpar exposure and an increased risk of seladelpar-related adverse reactions Details Seladelpar Letermovir Injection Prevymis Increased seladelpar exposure Details

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