Cefepime Injection

38 interactions 169 cited references

Also sold as: Maxipime®

About Cefepime Injection

Cefepime injection is used to treat certain infections caused by bacteria including pneumonia, and skin, urinary tract, and kidney infections. Cefepime injection is used in combination with metronidazole (Flagyl) to treat abdominal (stomach area) infections. Cefepime injection is also used to treat patients who have fe… Read the full Cefepime Injection drug information page →

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Aug 10, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Amikacin Amikacin Liposome Amiloride Bendroflumethiazide Benzthiazide Bumetanide

37 Major 1 Moderate

All (38) Major (37) Moderate (1)

Major

Cefepime Injection Amikacin An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Amikacin Liposome An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Amiloride An increased risk of nephrotoxicity Details Cefepime Injection Bendroflumethiazide An increased risk of nephrotoxicity Details Cefepime Injection Benzthiazide An increased risk of nephrotoxicity Details Cefepime Injection Bumetanide Bumex An increased risk of nephrotoxicity Details Cefepime Injection Chlorothiazide Diuril An increased risk of nephrotoxicity Details Cefepime Injection Chlorthalidone Hemiclor An increased risk of nephrotoxicity Details Cefepime Injection Cholera Vaccine, Live Reduced immune response to the cholera vaccine Details Cefepime Injection Clopamide An increased risk of nephrotoxicity Details Cefepime Injection Cyclopenthiazide An increased risk of nephrotoxicity Details Cefepime Injection Cyclothiazide An increased risk of nephrotoxicity Details Cefepime Injection Diazoxide Proglycem An increased risk of nephrotoxicity Details Cefepime Injection Eplerenone Inspra An increased risk of nephrotoxicity Details Cefepime Injection Ethacrynic Acid Edecrin An increased risk of nephrotoxicity Details Cefepime Injection Etozolin An increased risk of nephrotoxicity Details Cefepime Injection Furosemide Disal An increased risk of nephrotoxicity Details Cefepime Injection Gentamicin An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Hydrochlorothiazide Inzirqo An increased risk of nephrotoxicity Details Cefepime Injection Hydroflumethiazide An increased risk of nephrotoxicity Details Cefepime Injection Indapamide An increased risk of nephrotoxicity Details Cefepime Injection Kanamycin An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Methyclothiazide An increased risk of nephrotoxicity Details Cefepime Injection Metolazone An increased risk of nephrotoxicity Details Cefepime Injection Neomycin An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Paromomycin An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Piretanide An increased risk of nephrotoxicity Details Cefepime Injection Plazomicin An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Quinethazone An increased risk of nephrotoxicity Details Cefepime Injection Spironolactone Aldactone An increased risk of nephrotoxicity Details Cefepime Injection Streptomycin An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Tobramycin Bethkis An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Cefepime Injection Torsemide Soaanz An increased risk of nephrotoxicity Details Cefepime Injection Triamterene Dyrenium An increased risk of nephrotoxicity Details Cefepime Injection Trichlormethiazide An increased risk of nephrotoxicity Details Cefepime Injection Warfarin Coumadin An increased risk of bleeding Details Cefepime Injection Xipamide An increased risk of nephrotoxicity Details

Moderate

Cefepime Injection Typhoid Vaccine, Live Vivotif A decreased immunological response to the typhoid vaccine Details

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