Probucol

52 interactions 3 explained in plain English
Dr. Brian Staiger, PharmD, BCPS
Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Foscarnet Injection Moxifloxacin Lenvatinib Histrelin Implant Octreotide Oxaliplatin Injection
1 Contraindicated 49 Major 2 Moderate
All (52) Contraindicated (1) Major (49) Moderate (2)

Contraindicated

Probucol Foscarnet Injection Foscavir An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details

Major

Probucol Sertraline Explained An increased risk of QT interval prolongation Details Probucol Buprenorphine Belbuca Explained An increased risk of QT interval prolongation Details Probucol Relugolix Orgovyx Explained Increased risk of QT interval prolongation Details Probucol Amisulpride Injection Barhemsys Increased risk of serious ventricular arrhythmias such as torsades de pointes Details Probucol Arsenic Trioxide Trisenox An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Aripiprazole Injection Abilify An increased risk of QT interval prolongation Details Probucol Arsenic Trioxide Injection Trisenox An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Asenapine Transdermal Patch Secuado Increased risk of QT interval prolongation Details Probucol Azithromycin AzaSite An increased risk of QT interval prolongation and torsade de pointes Details Probucol Anagrelide Agrylin Increased risk of QT interval prolongation Details Probucol Bedaquiline Sirturo Increased risk of QT interval prolongation Details Probucol Chloroquine Aralen® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Dasatinib Phyrago An increased risk of QT interval prolongation Details Probucol Degarelix Injection Firmagon Increased risk of QT interval prolongation Details Probucol Deutetrabenazine Austedo An increased risk of QT interval prolongation Details Probucol Disopyramide Norpace An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Dofetilide Tikosyn An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Dolasetron Anzemet An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Dolasetron Injection Anzemet An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Encorafenib Braftovi Increased risk of QT interval prolongation Details Probucol Entrectinib Rozlytrek An increased risk of QT interval prolongation Details Probucol Flecainide Tambocor® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Fostemsavir Rukobia Increased risk of torsade de pointes Details Probucol Gemifloxacin Factive An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Glasdegib Daurismo Increased risk of QT interval prolongation Details Probucol Goserelin Implant Zoladex Increased risk of QT interval prolongation Details Probucol Histrelin Implant Supprelin Increased risk of QT interval prolongation Details Probucol Hydroxychloroquine Plaquenil Increased risk of QT interval prolongation Details Probucol Inotuzumab Ozogamicin Injection Besponsa Increased risk of QT interval prolongation Details Probucol Isradipine DynaCirc® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Ivabradine Corlanor Increased risk of QT prolongation Details Probucol Ketoconazole Topical Extina® Foam Increased risk of QT interval prolongation Details Probucol Lefamulin Xenleta Increased risk of QT interval prolongation Details Probucol Lenvatinib Lenvima Increased risk of QT-interval prolongation Details Probucol Levofloxacin Levaquin Increased risk of QT interval prolongation Details Probucol Levofloxacin Injection Levaquin Increased risk of QT interval prolongation Details Probucol Loperamide Diamode An increased risk of QT interval prolongation, which may increase risk of cardiotoxicity (torsade de pointes, cardiac arrest) Details Probucol Mefloquine Lariam® An increased risk of cardiotoxicity (QT prolongation, torsades de pointes, cardiac arrest) Details Probucol Metronidazole Flagyl An increased risk of QT interval prolongation Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist
Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.