Meptazinol

21 interactions 2 explained in plain English

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 4, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Acetaminophen And Codeine Levodopa Oral Inhalation Metoclopramide Nasal Spray Nalbuphine Injection Cetirizine Injection Hydromorphone Injection

20 Major 1 Moderate

All (21) Major (20) Moderate (1)

Major

Meptazinol Acetaminophen And Codeine Capital® & Codeine Explained An increased risk of hypotension, respiratory depression, profound sedation, coma and reduced analgesic effect or precipitation of... Details Meptazinol Buprenorphine Belbuca Explained Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome and respiratory depr... Details Meptazinol Butorphanol Injection Butorphic Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Meptazinol Butorphanol Nasal Spray Stadol® NS Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Meptazinol Cetirizine Injection Aller-Tec Increased risk of CNS depression Details Meptazinol Cetirizine Ophthalmic Zerviate Increased risk of CNS depression Details Meptazinol Diazepam Nasal Spray Valtoco Increased risk of CNS depression Details Meptazinol Diazepam Rectal Diastat Increased risk of CNS depression Details Meptazinol Esketamine Nasal Spray Spravato Increased risk of sedation Details Meptazinol Fentanyl Transdermal Patch Duragesic® Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Meptazinol Hydromorphone Injection Dilaudid Reduced analgesic effect or precipitation of withdrawal symptoms and an increased risk of serotonin syndrome Details Meptazinol Hydromorphone Rectal available generically Reduced analgesic effect or precipitation of withdrawal symptoms and an increased risk of serotonin syndrome Details Meptazinol Lacosamide Injection Motpoly An increased risk of CNS depression Details Meptazinol Levodopa Oral Inhalation Inbrija An increased risk of CNS depression Details Meptazinol Metoclopramide Injection Gimoti Increased risk of CNS depression Details Meptazinol Metoclopramide Nasal Spray Gimoti Increased risk of CNS depression Details Meptazinol Midazolam Nasal Spray Nayzilam Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Meptazinol Midazolam Injection Nayzilam Increased risk of hypoventilation, airway obstruction, desaturation, or apnea Details Meptazinol Morphine Injection Astramorph® PF Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details Meptazinol Nalbuphine Injection Nubain® Reduced analgesic effect or precipitation of withdrawal symptoms, and an increased risk of serotonin syndrome Details

Moderate

Meptazinol Clonidine Transdermal Patch Catapres An increased risk of sedation and somnolence Details

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Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.